Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8241125 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HCAR2KMT2ACYP3A4KDM4E | |
| SCHEMBL8115614 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HCAR2KMT2ACYP3A4KDM4E | |
| Nitrous Acid SCHEMBL7868432 | 0.88 | HCAR2 (0.38) | ALDH1A1HCAR2KMT2ACYP3A4KDM4E | |
| SCHEMBL5892165 | 0.81 | CA1 (0.44) | HCAR2KMT2A | |
| SCHEMBL17789740 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPTTDP1 | |
| SCHEMBL776266 | 0.81 | KMT2A (0.46) | ALDH1A1HCAR2KMT2AKDM4EGMNN | |
| SCHEMBL6670749 | 0.80 | LMNA (0.41) | ALDH1A1KMT2ACYP3A4KDM4ELMNA | |
| SCHEMBL2476595 | 0.79 | HCAR2 (0.40) | ALDH1A1HCAR2KMT2AKDM4EGMNN | |
| SCHEMBL24335753 | 0.79 | CYP19A1 (0.40) | ALDH1A1CYP3A4POLBMAPTHPGD | |
| SCHEMBL8551002 | 0.79 | ADRB2 (0.43) | ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250230170-A1 | Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | KANCERA AB (SE) | 2025-07-17 | — | — | US | disclosed |
| US-12264165-B2 | Process for the stereoselective preparation of chiral 2-[(hetero) arylalkylsulfanyl]pyrimidines and products obtainable therefrom | KANCERA AB (SE) | 2025-04-01 | — | — | US | disclosed |
| US-20230322807-A1 | Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | KANCERA AB (SE) | 2023-10-12 | — | — | US | disclosed |
| US-11691988-B2 | Process for the stereoselective preparation of chiral 2-[(hetero)arylalkylsulfanyl]pyrimidines and products obtainable therefrom | KANCERA AB (SE) | 2023-07-04 | — | — | US | disclosed |
| US-20230068240-A1 | A Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | KANCERA AB (SE) | 2023-03-02 | — | — | US | disclosed |
| US-11542281-B2 | Process for the steroselective preparation of chiral 2- [(hetero)arylalkylsulfanyl] pyrimidines and products obtainable therefrom | KANCERA AB (SE) | 2023-01-03 | — | — | US | disclosed |
| US-11450445-B2 | Electroconductive film and method for manufacturing electroconductive pattern | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2022-09-20 | — | — | US | disclosed |
| US-20210188873-A1 | A Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | KANCERA AB (SE) | 2021-06-24 | — | — | US | disclosed |
| CN-112218853-A | Process for the stereoselective preparation of chiral 2- [ (hetero) aralkylthio ] pyrimidines and products obtainable therefrom | 坎塞拉有限公司 | 2021-01-12 | — | — | CN | disclosed |
| US-20200303086-A1 | ELECTROCONDUCTIVE FILM AND METHOD FOR MANUFACTURING ELECTROCONDUCTIVE PATTERN | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2020-09-24 | — | — | US | disclosed |
| US-9713619-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-07-25 | — | — | US | disclosed |
| WO-2016092478-A1 | PROCESS FOR PREPARATION OF LULICONAZOLE | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2016-06-16 | — | — | WO | disclosed |
| US-8912330-B2 | Azaindole derivatives as kinase inhibitors | ARIAD PHARMACEUTICALS, INC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-20110294806-A1 | AZAINDOLE DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMACEUTICALS, INC. (US) | 2011-12-01 | — | — | US | disclosed |
| US-6346540-B1 | SUBSTANCE P ANTAGONISTS FOR TREATING CENTRAL NERVOUS SYSTEM, PSYCHOLOGICAL AND BRAIN DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-02-12 | — | — | US | disclosed |
| EP-0855999-B1 | 1-(1,2-DISUBSTITUTED PIPERIDINYL)-4-SUBSTITUTED PIPERIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2001-10-04 | — | — | EP | disclosed |
| US-6169097-B1 | 1-(1,2-Disubstituted piperidinyl)-4-substituted piperidine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-01-02 | — | — | US | disclosed |
| EP-0855999-A1 | 1-(1,2-DISUBSTITUTED PIPERIDINYL)-4-SUBSTITUTED PIPERIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997024324-A1 | 1-(1,2-DISUBSTITUTED PIPERIDINYL)-4-SUBSTITUTED PIPERIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-07-10 | — | — | WO | disclosed |
| US-5446011-A | Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid | RICOH COMPANY, LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322807-A1 | Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | CYP2S1, CYP2B6, CYP2F1 | ALDH1A1 333/4885HCAR2 1592/4885KMT2A 4025/4885 |
| US-12264165-B2 | Process for the stereoselective preparation of chiral 2-[(hetero) arylalkylsulfanyl]pyrimidines and products obtainable therefrom | CYP2B6, CYP2S1, CYP2D6 | ALDH1A1 306/4885HCAR2 1026/4885KMT2A 4060/4885 |
| US-11542281-B2 | Process for the steroselective preparation of chiral 2- [(hetero)arylalkylsulfanyl] pyrimidines and products obtainable therefrom | CYP2S1, CYP2B6, CYP2F1 | ALDH1A1 333/4885HCAR2 1592/4885KMT2A 4025/4885 |
| US-20210188873-A1 | A Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | CYP2S1, CYP2B6, TYMS | ALDH1A1 272/4885HCAR2 1661/4885KMT2A 4093/4885 |
| US-20230068240-A1 | A Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | CYP2S1, CYP2B6, TYMS | ALDH1A1 272/4885HCAR2 1661/4885KMT2A 4093/4885 |
| US-20110294806-A1 | AZAINDOLE DERIVATIVES AS KINASE INHIBITORS | ABL1, CDKN1A, MAP3K13 | ALDH1A1 2111/4885HCAR2 2658/4885KMT2A 408/4885 |
| US-20250230170-A1 | Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | CYP2S1, CYP2B6, CYP2F1 | ALDH1A1 333/4885HCAR2 1592/4885KMT2A 4025/4885 |
| US-11691988-B2 | Process for the stereoselective preparation of chiral 2-[(hetero)arylalkylsulfanyl]pyrimidines and products obtainable therefrom | CYP2B6, CYP2S1, CYP2D6 | ALDH1A1 306/4885HCAR2 1026/4885KMT2A 4060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.