Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 7/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028753 | 0.80 | HIF1A (0.52) | FFAR1FBP1HCAR2MEN1KMT2A | |
| SCHEMBL5348298 | 0.69 | GPR55 (0.49) | MEN1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL2573343 | 0.67 | FFAR1 (0.53) | FFAR1MEN1POLBKMT2APTGES | |
| SCHEMBL9752926 | 0.66 | FFAR1 (1.00) | FFAR1FBP1MEN1CYP3A4KMT2A | |
| SCHEMBL5341413 | 0.66 | CYP3A4 (0.46) | MEN1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL5914907 | 0.65 | ALDH1A1 (0.53) | HCAR2MEN1KMT2AHIF1AEPAS1 | |
| SCHEMBL5914896 | 0.64 | ALDH1A1 (0.52) | FBP1HCAR2MEN1POLBCYP3A4 | |
| SCHEMBL7607429 | 0.64 | FFAR1 (0.53) | FFAR1MEN1POLBKMT2A | |
| SCHEMBL22840392 | 0.63 | MAOB (0.67) | POLBCYP3A4MAOB | |
| Phloroisobutyrophenone SCHEMBL2150396 | 0.63 | FFAR1 (0.68) | FFAR1MEN1POLBCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013478-A1 | Calanolide analogues and methods of their use | SARAWAK MEDICHEM PHARMACEUTICALS,INC. | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013478-A1 | Calanolide analogues and methods of their use | HAVCR2, ZC3HAV1, CYP51A1 | FFAR1 4504/4885FBP1 2559/4885HCAR2 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.