Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SCN4A | P35499 | 4/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10562086 | 0.88 | MTNR1A (0.57) | LMNASCN4AMAOAPTGS1CYP2C9 | |
| SCHEMBL9808111 | 0.85 | LMNA (0.56) | LMNASCN4AKCNA3MAOAPTGS1 | |
| Trifluoroacetic Acid SCHEMBL2335690 | 0.83 | HDAC1 (0.47) | LMNASCN4ACYP2C9CYP2C19PPARG | |
| SCHEMBL421712 | 0.81 | LMNA (0.63) | LMNASCN4AKCNA3MAOAPTGS1 | |
| SCHEMBL27608630 | 0.81 | LMNA (0.52) | LMNASCN4AKCNA3MAOAPTGS1 | |
| SCHEMBL20379107 | 0.81 | LMNA (0.63) | LMNASCN4AKCNA3MAOAPTGS1 | |
| SCHEMBL9123715 | 0.81 | LMNA (0.63) | LMNASCN4AKCNA3MAOAPTGS1 | |
| SCHEMBL7100611 | 0.81 | LMNA (0.52) | LMNASCN4AKCNA3MAOAPTGS1 | |
| SCHEMBL15349936 | 0.79 | LMNA (0.50) | LMNASCN4AKCNA3MAOAPTGS1 | |
| SCHEMBL9486396 | 0.78 | LMNA (0.53) | LMNASCN4AKCNA3MAOAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210124-A2 | TARGETING MULTIMERIC IMAGING AGENTS THROUGH MULTILOCUS BINDING | Epix Medical, Inc. (US) | 2002-06-05 | — | — | EP | disclosed |
| US-6313305-B1 | ANTIBIOTICS, BACTERICIDES | HOECHST MARION ROUSSEL (FR) | 2001-11-06 | — | — | US | disclosed |
| WO-2001008712-A2 | TARGETING MULTIMERIC IMAGING AGENTS THROUGH MULTILOCUS BINDING | EPIX MEDICAL, INC. (US) | 2001-02-08 | — | — | WO | disclosed |
| US-5936083-A | BACTERICIDES | Uclaf, Roussel (FR) | 1999-08-10 | — | — | US | disclosed |
| US-5883248-A | QUATERNARY AMMONIUM INTERMEDIATES | ROUSSEL UCLAF (FR) | 1999-03-16 | — | — | US | disclosed |
| US-5763617-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5728828-A | A 3-(3-CHLORO- OR IODOPROP-1-EN-1-YL),7-(2-AMINOTHIAZOL-4-YL) ((CARBOXY)(PHENYL)METHOXYIMINO)ACETAMIDO-3-CEPHEM; GRAMNEGATIVE AND -POSITIVE BACTERIA, ESP. ANTIBIOTIC-RESISTANCE STAPHYLOCOCCUS | ROUSSEL UCLAF (FR) | 1998-03-17 | — | — | US | disclosed |
| US-5712266-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-01-27 | — | — | US | disclosed |
| US-5710147-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1998-01-20 | — | — | US | disclosed |
| US-5621095-A | BACTERICIDES | ROUSSEL UCLAF (FR) | 1997-04-15 | — | — | US | disclosed |
| US-5587372-A | BACERICIDES | ROUSSEL UCLAF (FR) | 1996-12-24 | — | — | US | disclosed |
| US-5541318-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1996-07-30 | — | — | US | disclosed |
| US-5538963-A | BACTERICIDE ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1996-07-23 | — | — | US | disclosed |
| US-5455238-A | Bactericides | ROUSSEL UCLAF (FR) | 1995-10-03 | — | — | US | disclosed |
| US-5416080-A | Cephalosporins | ROUSSEL-UCLAF (FR) | 1995-05-16 | — | — | US | disclosed |
| US-5397779-A | Cephalosporins | ROUSSEL-UCLAF (FR) | 1995-03-14 | — | — | US | disclosed |
| US-5378697-A | BACTERICIDES | ROUSSEL-UCLAF (FR) | 1995-01-03 | — | — | US | disclosed |
| US-5373001-A | Antibiotics | ROUSSEL UCLAF (FR) | 1994-12-13 | — | — | US | disclosed |
| EP-0115969-A1 | Penem compounds, their preparation , formulations containing the same and their use in combating bacteria | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1984-08-15 | — | — | EP | disclosed |