Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10562086 | 0.84 | MTNR1A (0.57) | LMNAPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL7688616 | 0.83 | LMNA (0.56) | LMNAPPARGPPARAMTNR1AMTNR1B | |
| Trifluoroacetic Acid SCHEMBL11354737 | 0.77 | ALOX15 (0.77) | HDAC1HDAC2LMNAPPARGALOX15 | |
| Phenoxypropazine SCHEMBL20268628 | 0.76 | MAOA (0.73) | LMNAMTNR1AMTNR1BCYP2C19CYP2D6 | |
| SCHEMBL3728369 | 0.74 | PPARG (0.54) | LMNAPPARGPPARAMTNR1AMTNR1B | |
| Trifluoroacetic Acid SCHEMBL6382769 | 0.74 | ALOX15 (0.55) | HDAC1HDAC2ALOX15MLYCD | |
| Trifluoroacetic Acid SCHEMBL6382776 | 0.74 | TAAR1 (0.68) | HDAC1HDAC2MTNR1AMTNR1B | |
| Diphenylether SCHEMBL8363381 | 0.73 | LTA4H (0.57) | HDAC1HDAC2PPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL21694066 | 0.72 | HDAC1 (0.47) | HDAC1HDAC2MTNR1AMTNR1BALOX15 | |
| Anisole SCHEMBL2335694 | 0.71 | CA4 (0.52) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071761-B2 | Substrates for beta-lactamase and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-06 | — | — | US | disclosed |
| EP-1405922-B1 | Substrates for beta-lactamase and uses thereof | UNIV CALIFORNIA (US) | 2011-08-24 | — | — | EP | disclosed |
| US-20070184513-A1 | Substrates for beta-lactamase and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-09 | — | — | US | disclosed |
| US-7157575-B2 | Substrates for β-lactamase and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-01-02 | — | — | US | disclosed |
| US-20030119085-A1 | Substrates for beta-lactamase and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-06-26 | — | — | US | disclosed |
| US-20020198254-A1 | Polyamide analogs | GENELABS TECHNOLOGIES, INC. | 2002-12-26 | — | — | US | disclosed |
| US-6472205-B1 | EXPRESSION CONTROL SEQUENCES ADAPTED FOR FUNCTION IN EUKARYOTIC CELL, OPERABLY LINKED TO SEQUENCE CODING CYTOSOLIC BETA-LACTAMASE; SCREENING BY CONTACTING HOST CELL WITH MEMBRANE PERMEABLE, FLUORESCENT SUBSTRATE OF BETA-LACTAMASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-10-29 | — | — | US | disclosed |
| WO-2002062755-A2 | POLYAMIDE ANALOGS AS DNA MINOR GROOVE BINDERS | GENELABS TECHNOLOGIES, INC. (US) | 2002-08-15 | — | — | WO | disclosed |
| US-6291162-B1 | DETERMINING AMOUNT OF LACTAMASE ACTIVITY; TRANSFECTING CELLS WITH A NUCLEIC ACID HAVING AN EXPRESSION CONTROL SEQUENCE LINKED TO A SECRETION DEFECTIVE SEQUENCE; MIXING CELLS WITH LACTAMASE SUBSTRATE; DETERMINE AMOUNT OF CLEAVED SUBSTRATE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-09-18 | — | — | US | disclosed |
| US-5955604-A | Substrates for β-lactamase and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-09-21 | — | — | US | disclosed |
| US-5741657-A | MEASURING GENE EXPRESSION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-21 | — | — | US | disclosed |
| US-4631270-A | THIOMETHYLENE REPLACEMENTS | RESEARCH CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119085-A1 | Substrates for beta-lactamase and uses thereof | CMBL, GLB1, BBOX1 | HDAC1 2022/4885HDAC2 1783/4885LMNA 444/4885 |
| US-20020198254-A1 | Polyamide analogs | CYP51A1, HDAC6, ERG28 | HDAC1 376/4885HDAC2 670/4885LMNA 1778/4885 |
| US-20070184513-A1 | Substrates for beta-lactamase and uses thereof | CMBL, DBH, NCEH1 | HDAC1 1603/4885HDAC2 905/4885LMNA 1658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.