Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688642 | 0.89 | GRM5 (0.36) | GRM5HTR5ASMOHPGDHTT | |
| SCHEMBL7687213 | 0.88 | HTR5A (0.38) | GRM5HTR5ASMOHPGDHTT | |
| SCHEMBL7910781 | 0.86 | GRM5 (0.39) | GRM5SMOADCY10FPR2PROKR1 | |
| SCHEMBL7687095 | 0.84 | S1PR1 (0.44) | LMNAKMT2A | |
| SCHEMBL7684696 | 0.76 | S1PR1 (0.44) | LMNAKMT2A | |
| SCHEMBL7904400 | 0.76 | SMO (0.39) | GRM5SMOHPGDHTTHSD17B10 | |
| SCHEMBL7687299 | 0.75 | GRM5 (0.35) | GRM5SMOHPGDHTTHSD17B10 | |
| SCHEMBL7690463 | 0.74 | TGFBR1 (0.34) | GRM5SMOHPGDHTTHSD17B10 | |
| SCHEMBL27532004 | 0.74 | GRM5 (0.33) | GRM5SMOHPGDHTTHSD17B10 | |
| SCHEMBL27676266 | 0.73 | CYP1A2 (0.45) | GRM5HPGDHSD17B10DHODHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020055639-A1 | Pyrazole derivatives as herbicides | NEBEL KURT (CH) | 2002-05-09 | — | — | US | disclosed |
| US-6274536-B1 | CROPS, AGRICULTURE; PRE- AND POSTEMERGENCE | SYNGENTA CROP PROTECTION, INC. | 2001-08-14 | — | — | US | disclosed |
| US-6204221-B1 | Herbicides | SYNGENTA CROP PROTECTION, INC. | 2001-03-20 | — | — | US | disclosed |
| EP-0966461-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | Novartis AG (CH) | 1999-12-29 | — | — | EP | disclosed |
| CN-1237166-A | Pyrazole derivatives useful as herbicides | NOVARTIS AG (CH) | 1999-12-01 | — | — | CN | disclosed |
| WO-1998042698-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | NOVARTIS AG (CH) | 1998-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055639-A1 | Pyrazole derivatives as herbicides | CBR3, HCN1, HCN2 | GRM5 1578/4885HTR5A 1650/4885SMO 3742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.