SCHEMBL7688909

SCHEMBL7688909

O=CNS(=O)(=O)CC1CCC1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 3/20 0.43
ADH1C P00326 3/20 0.43
ADH1A P07327 3/20 0.43
ADH7 P40394 3/20 0.43
ADH4 P08319 1/20 0.43
ACLY P53396 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7689062 0.91 ADH1B (0.32) ADH1BADH1CADH1AADH7ADH4
SCHEMBL7692423 0.79 ADH1B (0.41) ADH1BADH1CADH1AADH7ADH4
SCHEMBL7688952 0.70 ADH1B (0.30) ADH1BADH1CADH1AADH7ADH4
SCHEMBL23868226 0.70 ACACB (0.38) ADH1BADH1CADH1AADH7ADH4
SCHEMBL7688908 0.70 ACLY (0.36) ADH1BADH1CADH1AADH7ADH4
SCHEMBL10154033 0.68 JAK1 (0.39) ADH1BADH1CADH1AADH7ADH4
SCHEMBL19808141 0.68 ALDH1A1 (0.40) ACLY
SCHEMBL7692601 0.67 ALDH1A1 (0.31)
SCHEMBL22492233 0.67 CA2 (0.37) ADH1BADH1CADH1AADH7ADH4
SCHEMBL9700507 0.67 ADH1B (0.35) ADH1BADH1CADH1AADH7ADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002000622-A2 AMINOALCOHOL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-01-03 WO disclosed