Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695315 | 0.80 | TAS1R3 (0.52) | TAS1R3TAS1R1ATM | |
| SCHEMBL2830730 | 0.79 | ATM (0.53) | OPRK1ATM | |
| SCHEMBL2830729 | 0.79 | ATM (0.53) | OPRK1ATM | |
| SCHEMBL17706119 | 0.74 | SMN1; SMN2 (0.51) | MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL19602594 | 0.74 | SMN1; SMN2 (0.51) | MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL17790212 | 0.74 | SMN1; SMN2 (0.51) | MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL11067823 | 0.73 | MAPK1 (0.41) | OPRK1TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL5164472 | 0.72 | ALDH1A1 (0.57) | TAAR1KMT2A | |
| SCHEMBL5164476 | 0.72 | ALDH1A1 (0.57) | TAAR1KMT2A | |
| SCHEMBL23470280 | 0.72 | ATM (0.54) | OPRK1MEN1KMT2ASMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339159-B1 | REACTING AN ALDEHYDE COMPOUND, AN AMINO COMPOUND AND HYDROGEN CYANATE IN THE PRESENCE OF A CHIRAL ZIRCONIUM CATALYST OBTAINED BY MIXING ZIRCONIUM ALKOXIDE WITH OPTICALLY ACTIVE BINAPHTHOL COMPOUND TO FORM ALPHA-AMINONITRILE | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2002-01-15 | — | — | US | disclosed |