SCHEMBL7689348

SCHEMBL7689348

CS(=O)(=O)Oc1ccc(S(=O)(=O)C(=[N+]=[N-])S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.38
MMP7 P09237 2/20 0.38
MMP9 P14780 2/20 0.38
MMP14 P50281 2/20 0.38
MMP1 P03956 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 4/20 0.35
CA2 P00918 3/20 0.35
CA12 O43570 1/20 0.35
ADAMTS4 O75173 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
HTT P42858 2/20 0.34
LMNA P02545 2/20 0.34
PPARG P37231 2/20 0.34
RAB9A P51151 2/20 0.34
MAPT P10636 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL384279 0.94 MMP2 (0.42) MMP2MMP7MMP9MMP14MMP1
SCHEMBL7688694 0.88 CA2 (0.42) MMP2MMP7MMP9MMP14MMP1
SCHEMBL7694841 0.88 MMP2 (0.40) MMP2MMP7MMP9MMP14MMP1
SCHEMBL7690783 0.86 TDP1 (0.54) TDP1KMT2AMEN1ALDH1A1CA2
SCHEMBL7696470 0.85 MMP2 (0.42) MMP2MMP7MMP9MMP14TDP1
SCHEMBL3166497 0.84 KMT2A (0.48) MMP2MMP9MMP14MMP1MMP8
SCHEMBL7689322 0.84 ALDH1A1 (0.38) MMP2MMP7MMP9MMP14MMP1
SCHEMBL7695842 0.84 CA1 (0.46) MMP2MMP7MMP9MMP14MMP1
SCHEMBL7690064 0.84 ALDH1A1 (0.40) MMP2MMP7MMP9MMP14MMP1
SCHEMBL65095 0.82 SMN1; SMN2 (0.46) MMP2MMP9MMP1TDP1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6338931-B1 PHOTOACID GENERATOR OF SULFONYLDIAZOMETHANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-01-15 US disclosed