Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76595 | 0.91 | KCNK3 (0.50) | NPC1RAB9AKCNK3KCNK9SMN1; SMN2 | |
| SCHEMBL76387 | 0.87 | KCNK3 (0.47) | NPC1RAB9AKCNK3KCNK9PYGL | |
| SCHEMBL10227846 | 0.85 | ABCB1 (0.59) | NPC1RAB9AABCB1KCNK3KCNK9 | |
| SCHEMBL77944 | 0.82 | RAB9A (0.45) | NPC1RAB9AKCNK3KCNK9SMN1; SMN2 | |
| SCHEMBL10227845 | 0.77 | KCNK3 (0.54) | NPC1RAB9AABCB1KCNK3KCNK9 | |
| SCHEMBL10720290 | 0.73 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL669093 | 0.73 | ABCB1 (0.51) | NPC1RAB9AABCB1 | |
| SCHEMBL8461192 | 0.72 | ABCB1 (0.81) | ABCB1 | |
| SCHEMBL32672049 | 0.72 | ABCB1 (0.81) | ABCB1 | |
| SCHEMBL10227844 | 0.72 | NPC1 (0.48) | NPC1RAB9AABCB1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129355-B2 | Nuclear receptor-based inducible gene expression system; modulating the expression of a gene in a host cell by introducing into the host cell a gene expression modulation system and activating that system using 5-ethyl-2,3-dihydro-benzo[1,4]dioxine-6-carboxylic acid (1-benzoyl-cyclopentyl)-amide | INTREXON CORPORATION (US) | 2012-03-06 | — | — | US | disclosed |