Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697719 | 0.84 | NPC1 (0.50) | TDP1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7698454 | 0.83 | NQO2 (0.45) | TDP1MAPTL3MBTL1LMNAMEN1 | |
| SCHEMBL7695424 | 0.81 | CYP1A2 (0.42) | MAPTGRM5LMNAMEN1KMT2A | |
| SCHEMBL7697161 | 0.81 | MAOA (0.43) | MAPTL3MBTL1MAOBMAOAGRM5 | |
| SCHEMBL7689877 | 0.81 | SMN1; SMN2 (0.43) | TDP1MAPTL3MBTL1MAOBMAOA | |
| SCHEMBL7698500 | 0.78 | SOD1 (0.44) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL7695317 | 0.77 | CYP2A6 (0.39) | TDP1MAPTL3MBTL1LMNACYP2C9 | |
| SCHEMBL7691393 | 0.76 | LMNA (0.54) | MAPTGAAL3MBTL1GRM5DHFR | |
| SCHEMBL7697058 | 0.74 | RAB9A (0.50) | TDP1MAPTGAAL3MBTL1DHFR | |
| SCHEMBL7694096 | 0.74 | NPC1 (0.50) | TDP1MAPTLMNACYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |