Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056735 | 0.78 | HPGD (0.45) | ALDH1A1LMNASMN1; SMN2POLBGALR2 | |
| SCHEMBL7135043 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2POLBGALR2 | |
| SCHEMBL9423139 | 0.69 | CYP1A2 (0.49) | ALDH1A1LMNASMN1; SMN2HPGDNPSR1 | |
| SCHEMBL3784882 | 0.67 | NPC1 (0.48) | ALDH1A1LMNASMN1; SMN2POLBGALR2 | |
| SCHEMBL1068721 | 0.67 | MAPT (0.47) | ALDH1A1LMNASMN1; SMN2HPGDKMT2A | |
| SCHEMBL12820656 | 0.66 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2POLBGALR2 | |
| SCHEMBL28465212 | 0.66 | FBP1 (0.73) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1650715 | 0.66 | CYP1A2 (0.49) | ALDH1A1LMNASMN1; SMN2HPGDKMT2A | |
| SCHEMBL954612 | 0.65 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2POLBGALR2 | |
| SCHEMBL4045293 | 0.65 | MEN1 (0.45) | ALDH1A1LMNAHSP90AA1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062755-A2 | POLYAMIDE ANALOGS AS DNA MINOR GROOVE BINDERS | GENELABS TECHNOLOGIES, INC. (US) | 2002-08-15 | — | — | WO | disclosed |