SCHEMBL769001

SCHEMBL769001

CC(=O)NC1C(C)OC(CO)C(OC2OC(CO)C(O)C(O)C2O)C1O

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 7/20 0.65
LGALS8 O00214 2/20 0.65
LGALS4 P56470 2/20 0.65
CD69 Q07108 1/20 0.51
ALDH1A1 P00352 1/20 0.50
THRB P10828 1/20 0.50
CHIA Q9BZP6 1/20 0.50
LGALS1 P09382 1/20 0.49
LGALS7; LGALS7B P47929 1/20 0.49
AMY2A P04746 2/20 0.48
MAPK1 P28482 2/20 0.48
LGALS9 O00182 1/20 0.48
AMY1A P0DUB6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15084197 1.00 LGALS3 (0.65) LGALS3LGALS8LGALS4CD69ALDH1A1
SCHEMBL10068129 1.00 LGALS3 (0.65) LGALS3LGALS8LGALS4CD69ALDH1A1
SCHEMBL13541588 1.00 LGALS3 (0.65) LGALS3LGALS8LGALS4CD69ALDH1A1
SCHEMBL15962542 1.00 LGALS3 (0.65) LGALS3LGALS8LGALS4CD69ALDH1A1
SCHEMBL12733135 1.00 LGALS3 (0.65) LGALS3LGALS8LGALS4CD69ALDH1A1
SCHEMBL24770581 1.00 LGALS3 (0.65) LGALS3LGALS8LGALS4CD69ALDH1A1
SCHEMBL18383019 1.00 LGALS3 (0.65) LGALS3LGALS8LGALS4CD69ALDH1A1
SCHEMBL18387251 1.00 LGALS3 (0.65) LGALS3LGALS8LGALS4CD69ALDH1A1
SCHEMBL22193219 1.00 LGALS3 (0.65) LGALS3LGALS8LGALS4CD69ALDH1A1
SCHEMBL23059762 0.98 LGALS3 (0.66) LGALS3LGALS8LGALS4CD69ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230304998-A1 CELLULAR MATERIAL DETECTION PROBES FluoretiQ Limited (GB) 2023-09-28 US disclosed
US-11214588-B2 Synthesis of oligosaccharides GLYCOM A/S (DK) 2022-01-04 US disclosed
US-20210308162-A1 NOVEL TLR4 INHIBITORS FOR THE TREATMENT OF HUMAN INFECTIOUS AND INFLAMMATORY DISORDERS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2021-10-07 US disclosed
US-10933077-B2 TLR4 inhibitors for the treatment of human infectious and inflammatory disorders University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2021-03-02 US disclosed
US-20200215486-A1 SYNTHESIS OF OLIGOSACCHARIDES GLYCOM A/S (DK) 2020-07-09 US disclosed
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2012-03-22 US disclosed
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11214588-B2 Synthesis of oligosaccharides MGAM, LCT, LPO LGALS3 969/4885LGALS8 348/4885LGALS4 577/4885
US-20210308162-A1 NOVEL TLR4 INHIBITORS FOR THE TREATMENT OF HUMAN INFECTIOUS AND INFLAMMATORY DISORDERS TLR4, TLR3, TLR1 LGALS3 487/4885LGALS8 431/4885LGALS4 203/4885
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF TLR3, TLR5, PARP15 LGALS3 399/4885LGALS8 1606/4885LGALS4 524/4885
US-10933077-B2 TLR4 inhibitors for the treatment of human infectious and inflammatory disorders TLR4, TLR3, TLR1 LGALS3 492/4885LGALS8 505/4885LGALS4 262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.