Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.65 |
| ▸ | CA2 | P00918 | 9/20 | 0.65 |
| ▸ | CA12 | O43570 | 6/20 | 0.65 |
| ▸ | CA7 | P43166 | 6/20 | 0.65 |
| ▸ | CA9 | Q16790 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693397 | 0.85 | MAPT (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7697739 | 0.84 | GUSB (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7694814 | 0.83 | DHFR (0.67) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7697068 | 0.83 | DHFR (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7695461 | 0.80 | ALDH1A1 (0.57) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28558189 | 0.75 | DHFR (0.81) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7690975 | 0.75 | ALDH1A1 (0.64) | CA1CA2ALDH1A1ALOX12MAPT | |
| SCHEMBL7695444 | 0.75 | ALDH1A1 (1.00) | ALDH1A1ALOX12MAPTADORA2BPOLB | |
| SCHEMBL10113224 | 0.75 | MAPT (0.82) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7691439 | 0.74 | CA12 (0.83) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |