Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524248 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL7518961 | 0.72 | ALDH1A1 (0.32) | ALDH1A1TSHRHSD17B10ALOX15APP | |
| SCHEMBL1551933 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL160506 | 0.70 | — | — | |
| SCHEMBL105204 | 0.70 | CA1 (0.48) | ALDH1A1MAPK1CYP3A4TDP1MAPT | |
| SCHEMBL2779576 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL2890570 | 0.69 | HRH3 (0.43) | ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL19917 | 0.68 | — | — | |
| SCHEMBL21590 | 0.68 | — | — | |
| SCHEMBL9127771 | 0.68 | ALDH1A1 (0.46) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436961-B1 | SUBSTANCE P RECEPTOR ANTAGONIST; 2-PHENYL-3-BENZYLAMINOPIPERIDINES | PFIZER INC | 2002-08-20 | — | — | US | claimed |