Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 2/20 | 0.46 |
| ▸ | QPCT | Q16769 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691063 | 0.92 | SOD1 (0.50) | SOD1QPCTALDH1A1KDM4EMAPK1 | |
| SCHEMBL7692769 | 0.87 | KDM4E (0.49) | SOD1QPCTALDH1A1KDM4EMAPK1 | |
| SCHEMBL7693923 | 0.85 | MAPK14 (0.45) | MAPK14 | |
| SCHEMBL7697564 | 0.82 | MAPK14 (0.41) | MAPK14 | |
| SCHEMBL7700675 | 0.82 | MAPK14 (0.43) | ALDH1A1KDM4EMAPTHPGDMAPK14 | |
| SCHEMBL7690441 | 0.81 | MAPK14 (0.47) | SMN1; SMN2MAPK14 | |
| SCHEMBL7691048 | 0.79 | MAPK14 (0.42) | ALDH1A1KDM4EMAPTRAB9ANPSR1 | |
| SCHEMBL7697861 | 0.79 | MAPK14 (0.47) | MAPTMAPK14 | |
| SCHEMBL7696568 | 0.78 | MAPK14 (0.41) | ALDH1A1KDM4EMAPTHPGDMAPK14 | |
| SCHEMBL7694525 | 0.78 | MAPK14 (0.39) | RAB9ANPC1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |