Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459530 | 0.84 | FOLH1 (0.37) | FOLH1ALDH1A1LMNATSHRPTPN1 | |
| SCHEMBL3459412 | 0.84 | FOLH1 (0.37) | FOLH1ALDH1A1LMNATSHRPTPN1 | |
| SCHEMBL5669568 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAHPGDTSHRHTT | |
| SCHEMBL6156562 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAHPGDTSHRHTT | |
| SCHEMBL7684484 | 0.80 | LMNA (0.33) | FOLH1ALDH1A1LMNAHPGDTSHR | |
| SCHEMBL8035923 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAHPGDTSHRHTT | |
| SCHEMBL10613851 | 0.78 | MEN1 (0.47) | ALDH1A1LMNATSHRMAPT | |
| SCHEMBL27869104 | 0.77 | ALDH1A1 (0.38) | FOLH1ALDH1A1LMNAHPGDTSHR | |
| SCHEMBL8227007 | 0.74 | ALDH1A1 (0.44) | FOLH1ALDH1A1LMNAHPGDTSHR | |
| SCHEMBL7691194 | 0.73 | ERCC5 (0.36) | FOLH1ALDH1A1LMNAPTPN1CLCN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407100-B1 | HORTICULTURE, AGRICULTURE, WOOD PRESERVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-18 | — | — | US | disclosed |
| US-6355634-B1 | OXIME DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-12 | — | — | US | disclosed |