Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539853 | 0.91 | NPC1 (0.44) | MAPTHPGDRAB9AMEN1KMT2A | |
| SCHEMBL6539755 | 0.91 | NPC1 (0.44) | MAPTHPGDRAB9AMEN1KMT2A | |
| SCHEMBL6538741 | 0.86 | PPARA (0.46) | MAPTHPGDRAB9AMEN1KMT2A | |
| SCHEMBL6538746 | 0.86 | PPARA (0.46) | MAPTHPGDRAB9AMEN1KMT2A | |
| SCHEMBL6541438 | 0.83 | CAPN1 (0.38) | MAPTHPGDKMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL6541442 | 0.83 | CAPN1 (0.38) | MAPTHPGDKMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL6541226 | 0.83 | ALDH1A1 (0.39) | MAPTHPGDTSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL6541124 | 0.83 | NAMPT (0.42) | ALDH1A1HSD17B10 | |
| SCHEMBL6541119 | 0.83 | NAMPT (0.42) | ALDH1A1HSD17B10 | |
| SCHEMBL6541230 | 0.83 | ALDH1A1 (0.39) | MAPTHPGDTSHRSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |