Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700375 | 0.80 | RAB9A (0.38) | TSHRLMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL20570815 | 0.78 | TSHR (0.53) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL27970370 | 0.77 | TSHR (0.51) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL22612420 | 0.75 | NPC1 (0.33) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL8116755 | 0.74 | TSHR (0.49) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL29291579 | 0.74 | TSHR (0.54) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL29126825 | 0.73 | ALDH1A1 (0.55) | TSHRLMNACYP3A4L3MBTL1TDP1 | |
| SCHEMBL1126448 | 0.70 | ALDH1A1 (0.50) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL7416576 | 0.70 | LMNA (0.38) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL17519011 | 0.69 | RAB9A (0.51) | TSHRLMNACYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000614-A1 | ARYL COMPOUNDS, THEIR PREPARATION AND THEIR USE IN THERAPY | RIBOTARGETS LIMITED (GB) | 2002-01-03 | — | — | WO | disclosed |