Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30668214 | 1.00 | ADORA3 (0.45) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL18076173 | 0.81 | MKNK1 (0.51) | MKNK1MKNK2KDM4EALDH1A1NR3C2 | |
| SCHEMBL28777569 | 0.81 | GRM5 (0.50) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL231979 | 0.81 | KDM4E (0.61) | GRM5LMNAKDM4EALDH1A1KDM6B | |
| SCHEMBL29954072 | 0.81 | KDM4E (0.61) | GRM5LMNAKDM4EALDH1A1KDM6B | |
| SCHEMBL23874595 | 0.79 | GRM5 (0.43) | GRM5NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2275018 | 0.79 | KDM4E (0.59) | GRM5LMNAKDM4EALDH1A1KDM6B | |
| SCHEMBL30004144 | 0.79 | ALDH1A1 (0.50) | GRM5NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL1612977 | 0.79 | ALDH1A1 (0.50) | GRM5NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL31213280 | 0.79 | P2RX7 (0.49) | ADORA3GRM5KDM4ENR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112250622-B | Preparation method of 4-fluoropyridine-2-amine | 山东省海洋化工科学研究院 | 2022-05-27 | — | — | CN | claimed |
| CN-112552233-A | Synthetic method of 2-amino-4-fluoropyridine | 镇江卡博医药科技有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-112250622-A | Preparation method of 4-fluoropyridine-2-amine | 山东省海洋化工科学研究院 | 2021-01-22 | — | — | CN | claimed |
| CN-112250622-B | Preparation method of 4-fluoropyridine-2-amine | 山东省海洋化工科学研究院 | 2022-05-27 | — | — | CN | disclosed |
| CN-112552233-A | Synthetic method of 2-amino-4-fluoropyridine | 镇江卡博医药科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112552233-A | Synthetic method of 2-amino-4-fluoropyridine | 镇江卡博医药科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112250622-A | Preparation method of 4-fluoropyridine-2-amine | 山东省海洋化工科学研究院 | 2021-01-22 | — | — | CN | disclosed |
| US-6337368-B1 | WATER INSOLUBLE CARRIERS WITH P-NITROBENZOIC ACID, AROMATIC AMINES, AMIDES, SULFONAMIDES AND HYDRAZIDES | KANEKA CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-1008383-A1 | LIPOPROTEIN ADSORBENT AND LIPOPROTEIN ADSORBER MADE WITH THE USE OF THE SAME | KANEKA CORPORATION (JP) | 2000-06-14 | — | — | EP | disclosed |