Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | ASPH | Q12797 | 3/20 | 0.61 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.61 |
| ▸ | KDM5A | P29375 | 2/20 | 0.61 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.61 |
| ▸ | KDM6B | O15054 | 1/20 | 0.61 |
| ▸ | TET3 | O43151 | 1/20 | 0.61 |
| ▸ | KDM4A | O75164 | 1/20 | 0.61 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KDM5C | P41229 | 1/20 | 0.61 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.61 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.61 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.61 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.61 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.61 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.61 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.61 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954072 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL2275018 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL3223370 | 0.81 | KMO (0.65) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL23874595 | 0.81 | GRM5 (0.43) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL30004144 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL30668214 | 0.81 | ADORA3 (0.45) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL7692385 | 0.81 | ADORA3 (0.45) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL1612977 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL24572141 | 0.80 | KMO (0.62) | KDM4EALDH1A1ASPHKDM8KDM5A | |
| SCHEMBL30800092 | 0.79 | KMO (0.71) | KDM4EALDH1A1ASPHKDM8KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836306-A | Galactose glycoside derivatives as galectin-3 inhibitors | 株式会社蒂奥姆生物 | 2024-04-05 | — | — | CN | claimed |
| CN-112552233-A | Synthetic method of 2-amino-4-fluoropyridine | 镇江卡博医药科技有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-102105437-A | Adamantyl diamide derivatives and uses of same | LUNDBECK & CO AS H | 2011-06-22 | — | — | CN | claimed |
| US-20100022546-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2010-01-28 | — | — | US | claimed |
| EP-4724435-A1 | BIFUNCTIONAL AZINES CONJOGATES AS SELECTIVE DEGRADERS OF SMARCA2 AND THERAPEUTIC USES THEREOF | Nurix Therapeutics, Inc. (US) | 2026-04-15 | — | — | EP | disclosed |
| US-20260083851-A1 | POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2026-03-26 | — | — | US | disclosed |
| EP-4713320-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| EP-3710428-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-03-25 | — | — | EP | disclosed |
| US-12559462-B2 | Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250270172-A1 | Pyrimidine Derivatives As Modulators of the 5-HT2A Serotonin Receptor Useful For The Treatment of Disorders Related Thereto | ARENA PHARMACEUTICALS, INC. (US) | 2025-08-28 | — | — | US | disclosed |
| EP-4236937-B1 | PYRIMIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2025-07-23 | — | — | EP | disclosed |
| EP-4572759-A2 | THIAZOLE DERIVATIVES FOR THERAPEUTIC USE | Nimml Institute (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2011050316-A1 | MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | VANDERBILT UNIVERSITY (US) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011035174-A1 | SUBSTITUTED HETEROARYLAMINE CARBOXAMIDE ANALOGS AS MGLUR5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME | VANDERBILT UNIVERSITY (US) | 2011-03-24 | — | — | WO | disclosed |
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |
| US-6337368-B1 | WATER INSOLUBLE CARRIERS WITH P-NITROBENZOIC ACID, AROMATIC AMINES, AMIDES, SULFONAMIDES AND HYDRAZIDES | KANEKA CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-1008383-A1 | LIPOPROTEIN ADSORBENT AND LIPOPROTEIN ADSORBER MADE WITH THE USE OF THE SAME | KANEKA CORPORATION (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-5582817-A | ORGANOZINC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0583479-A1 | REMEDY FOR DERMATOPATHY AND METALLOTHIONEIN INDUCER | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270172-A1 | Pyrimidine Derivatives As Modulators of the 5-HT2A Serotonin Receptor Useful For The Treatment of Disorders Related Thereto | HTR2A, HTR5A, HTR1A | KDM4E 3934/4885ALDH1A1 768/4885ASPH 1161/4885 |
| US-20260083851-A1 | POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | ASGR1, FCGR2A, FCGR3B | KDM4E 4281/4885ALDH1A1 2349/4885ASPH 1493/4885 |
| US-12559462-B2 | Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto | HTR2C, HTR1A, HTR2A | KDM4E 4301/4885ALDH1A1 873/4885ASPH 3113/4885 |
| US-20100022546-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | QDPR, ADM2, PDE3B | KDM4E 2749/4885ALDH1A1 105/4885ASPH 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.