SCHEMBL76930

SCHEMBL76930

NS(=O)(=O)c1[c]cccc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 17/20 0.42
CA1 P00915 15/20 0.42
CA9 Q16790 12/20 0.42
CA12 O43570 9/20 0.42
CA7 P43166 6/20 0.42
CA4 P22748 5/20 0.42
CA5A P35218 5/20 0.42
CA6 P23280 4/20 0.42
CA5B Q9Y2D0 4/20 0.42
CA14 Q9ULX7 3/20 0.42
CA3 P07451 1/20 0.42
PLA2G7 Q13093 1/20 0.42
CA13 Q8N1Q1 1/20 0.42
CYP2C9 P11712 1/20 0.38
LMNA P02545 1/20 0.34
SCN2A Q99250 1/20 0.33
SOS1 Q07889 1/20 0.33
LDHA P00338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150811 0.80 HTR6 (0.38) CA2CA1CA9CA5A
SCHEMBL8387010 0.78 HTR6 (0.31) CA2CA1CA9CA5A
SCHEMBL1726647 0.76
SCHEMBL6135776 0.76
SCHEMBL219484 0.76 TSHR (0.42) CA2CA1LMNA
SCHEMBL77668 0.76 PTGS2 (0.33)
SCHEMBL600073 0.76 ALDH1A1 (0.42)
SCHEMBL1727931 0.76 ELANE (0.38)
SCHEMBL1727551 0.76
SCHEMBL4687573 0.74 CA2 (0.39) CA2CA1CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2484 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024133860-A1 SYNTHESIS OF SMALL MOLECULE AGONISTS OF NEUROPTROPHIN Oculis Operations Sàrl (CH) 2024-06-27 WO claimed
US-20230331715-A1 SPIRO[3.3]HEPTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION HOFFMANN-LA ROCHE INC. (US) 2023-10-19 US claimed
EP-4251615-A1 SPIRO[3.3]HEPTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION F. Hoffmann-La Roche AG (CH) 2023-10-04 EP claimed
CN-116406362-A Spiro [3.3] heptane derivatives for the treatment and prevention of hepatitis b virus infection 豪夫迈·罗氏有限公司 2023-07-07 CN claimed
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-05-25 US claimed
EP-4151621-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD THEREFOR AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-03-22 EP claimed
US-20220387385-A1 NEW TREATMENT REGIMENT FOR THE TREATMENT OF NEUROLOGICAL DISEASES OR CONDITIONS ACCURE THERAPEUTICS, S.L. (ES) 2022-12-08 US claimed
CN-115052595-A Novel therapeutic methods for treating neurological diseases or disorders 阿库尔疗法公司 2022-09-13 CN claimed
WO-2022112188-A1 SPIRO[3.3]HEPTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION F. HOFFMANN-LA ROCHE AG (CH) 2022-06-02 WO claimed
EP-3993784-A1 COMBINATION THERAPY METHODS, COMPOSITIONS AND KITS Accure Therapeutics, S.L. (ES) 2022-05-11 EP claimed
US-4283556-A Process for the manufacture of substantially pure 3-amino-4-alkoxy-acylanilides from 2,4-dinitrochlorobenzene TOMS RIVER CHEMICAL CORPORATION (US) 1981-08-11 US claimed
US-4275201-A Aryl substituted diketones STERLING DRUG INC. (US) 1981-06-23 US claimed
US-4247479-A REACTING THE OXIME HYDROCHLORIDE WITH THREE MOLES OF ACETIC ANHYDRIDE HOECHST AKTIENGESELLSCHAFT (DE) 1981-01-27 US claimed
US-4246284-A Aminosulfonyl-substituted aryloxyalkyl diketones STERLING DRUG INC. (US) 1981-01-20 US claimed
EP-0011048-A1 A process for the manufacture of substantially pure 3-amino-4-alkoxy-acylanilides from 2,4-dinitrochlorobenzene Toms River Chemical Corporation (US) 1980-05-14 EP claimed
US-RE29358-E ANTI-MALARIA AND ANTI-TUBERCULOSIS AGENTS AMERICAN CYANAMID COMPANY (US) 1977-08-16 US claimed
US-4024123-A TEXTILES DUSSY PAUL 1977-05-17 US claimed
US-4001204-A Magenta image-providing phenylazonaphthyl dues containing a morpholinyl of piperidine radical EASTMAN KODAK COMPANY (US) 1977-01-04 US claimed
US-3954476-A Diffusable dye-releasing compounds which are cleavable upon oxidation EASTMAN KODAK COMPANY (US) 1976-05-04 US claimed
US-3932380-A DIFFUSION TRANSFER COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1976-01-13 US claimed