Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | IAPP | P10997 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20848180 | 0.97 | TDP1 (0.47) | TDP1ALDH1A1FFAR3TSHRIAPP | |
| SCHEMBL9940199 | 0.92 | TDP1 (0.43) | TDP1ALDH1A1FFAR3TSHRIAPP | |
| SCHEMBL19396416 | 0.90 | TSHR (0.48) | TDP1ALDH1A1TSHR | |
| SCHEMBL15119310 | 0.90 | ALDH1A1 (0.41) | TDP1ALDH1A1TSHRCES2 | |
| SCHEMBL16298785 | 0.90 | TDP1 (0.41) | TDP1ALDH1A1FFAR3TSHRCES2 | |
| SCHEMBL11763603 | 0.89 | — | — | |
| SCHEMBL15223139 | 0.88 | TDP1 (0.39) | TDP1ALDH1A1 | |
| SCHEMBL19704889 | 0.88 | ALDH1A1 (0.39) | TDP1ALDH1A1TSHRCES2 | |
| SCHEMBL15223140 | 0.88 | TDP1 (0.39) | TDP1ALDH1A1TSHR | |
| SCHEMBL19704866 | 0.88 | ALDH1A1 (0.39) | TDP1ALDH1A1TSHRCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114660299-A | Biomarker and kit for diagnosing or preventing liver injury and application of biomarker and kit | 中南大学 | 2022-06-24 | — | — | CN | claimed |
| CN-114910571-A | Method and system for online analyzing sulfur-containing compounds in gas by flame photometry | 中国石油天然气股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| US-20020042407-A1 | Antiinflammatory agents; respiratory system disorders | DUKE UNIVERSITY | 2002-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042407-A1 | Antiinflammatory agents; respiratory system disorders | LPO, PRDX5, MPO | TDP1 2647/4885ALDH1A1 770/4885FFAR3 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.