Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 4/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | IAPP | P10997 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16298785 | 0.98 | TDP1 (0.41) | TDP1ALDH1A1HSD17B10CES2CES1 | |
| SCHEMBL7693105 | 0.92 | TDP1 (0.50) | TDP1ALDH1A1CES2CES1NAAA | |
| SCHEMBL20848180 | 0.90 | TDP1 (0.47) | TDP1ALDH1A1HSD17B10CES2CES1 | |
| SCHEMBL27506951 | 0.90 | HSD17B10 (0.39) | TDP1ALDH1A1HSD17B10CES2CES1 | |
| SCHEMBL28334432 | 0.87 | TDP1 (0.59) | TDP1ALDH1A1HSD17B10CES2NAAA | |
| SCHEMBL16968094 | 0.86 | TSHR (0.39) | TDP1ALDH1A1HSD17B10CES2NAAA | |
| Hydrochloric Acid SCHEMBL28339331 | 0.84 | TSHR (0.48) | TDP1ALDH1A1CES2CES1NAAA | |
| SCHEMBL13883578 | 0.84 | KMT2A (0.39) | TDP1ALDH1A1CES2NAAADGKA | |
| SCHEMBL15119310 | 0.83 | ALDH1A1 (0.41) | TDP1ALDH1A1CES2TSHR | |
| SCHEMBL19396416 | 0.83 | TSHR (0.48) | TDP1ALDH1A1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140371258-A1 | Water-Soluble Polymer Conjugates of Topotecan | NEKTAR THERAPEUTICS (US) | 2014-12-18 | — | — | US | disclosed |
| EP-2651875-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080264-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| US-20120046223-A1 | EXOGENOUSLY TRIGGERED CONTROLLED RELEASE MATERIALS AND USES THEREOF | SMARTCELLS, INC. | 2012-02-23 | — | — | US | disclosed |
| US-20110281791-A1 | CRYSTALLINE INSULIN-CONJUGATES | SMARTCELLS, INC. | 2011-11-17 | — | — | US | disclosed |
| US-20110275560-A1 | SYNTHETIC CONJUGATES AND USES THEREOF | SMARTCELLS, INC. | 2011-11-10 | — | — | US | disclosed |
| CN-1919942-A | Curable composition, ink composition, inkjet recording method | FUJI PHOTO FILM CO LTD (JP) | 2007-02-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275560-A1 | SYNTHETIC CONJUGATES AND USES THEREOF | SLC2A4, SLC2A8, CD44 | TDP1 2864/4885ALDH1A1 2321/4885HSD17B10 3774/4885 |
| US-20140371258-A1 | Water-Soluble Polymer Conjugates of Topotecan | TOP2A, TOP1, TOP2B | TDP1 89/4885ALDH1A1 3300/4885HSD17B10 2655/4885 |
| US-20110281791-A1 | CRYSTALLINE INSULIN-CONJUGATES | IAPP, INSR, GPR119 | TDP1 3291/4885ALDH1A1 4657/4885HSD17B10 683/4885 |
| US-20120046223-A1 | EXOGENOUSLY TRIGGERED CONTROLLED RELEASE MATERIALS AND USES THEREOF | CD63, NSF, MSN | TDP1 2749/4885ALDH1A1 3851/4885HSD17B10 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.