Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | IDO1 | P14902 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 9/20 | 0.44 |
| ▸ | LATS1 | O95835 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13158929 | 0.83 | RAB9A (1.00) | NPC1RAB9AALDH1A1ELANEGAA | |
| SCHEMBL3453705 | 0.77 | ELANE (0.73) | NPC1RAB9AALDH1A1ELANEGAA | |
| SCHEMBL7694055 | 0.72 | RAB9A (0.64) | NPC1RAB9AALDH1A1ELANEGAA | |
| SCHEMBL5489359 | 0.71 | MEN1 (0.49) | NPC1RAB9AIDO1ALDH1A1ELANE | |
| SCHEMBL5963788 | 0.71 | RAB9A (0.61) | NPC1RAB9AALDH1A1ELANEGAA | |
| SCHEMBL16247573 | 0.71 | IDO1 (1.00) | IDO1TDO2 | |
| SCHEMBL14228040 | 0.70 | IDO1 (0.64) | IDO1TDO2 | |
| SCHEMBL5821413 | 0.70 | TDO2 (0.42) | IDO1ALDH1A1ELANETDO2KDM4E | |
| SCHEMBL5316896 | 0.68 | ALDH1A1 (0.55) | NPC1RAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2658434 | 0.66 | NPC1 (1.00) | NPC1RAB9AALDH1A1ELANEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000040569-A9 | 2-AMINO-BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF OBESITY | ALIZYME THERAPEUTICS LTD (GB) | 2002-02-28 | — | — | WO | claimed |