Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 3/20 | 0.44 |
| ▸ | EDNRA | P25101 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DHPS | P49366 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | KLK3 | P07288 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423634 | 0.85 | FFAR1 (0.51) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL7700308 | 0.84 | DHPS (0.51) | EDNRBEDNRAALDH1A1MAPTMEN1 | |
| SCHEMBL1937757 | 0.80 | EDNRA (0.49) | EDNRBEDNRADHPS | |
| SCHEMBL7698527 | 0.79 | DHPS (0.65) | DHPS | |
| SCHEMBL7698526 | 0.78 | DHPS (0.46) | EDNRBEDNRADHPSKLK3 | |
| SCHEMBL4061462 | 0.78 | DHPS (0.49) | EDNRBEDNRAALDH1A1MAPTMEN1 | |
| SCHEMBL4060945 | 0.77 | DHPS (0.71) | EDNRBEDNRADHPS | |
| SCHEMBL28568819 | 0.76 | DHPS (0.59) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL7483960 | 0.75 | HTT (0.48) | ALDH1A1MAPTSMN1; SMN2KDM4EDHPS | |
| SCHEMBL5632966 | 0.74 | HTT (0.47) | ALDH1A1MAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083650-A1 | NOVEL SULFONYLAMINO-PYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-10-24 | — | — | WO | disclosed |