Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700308 | 0.92 | DHPS (0.51) | DHPS | |
| SCHEMBL7698526 | 0.84 | DHPS (0.46) | DHPS | |
| SCHEMBL4064097 | 0.83 | DHPS (0.74) | DHPS | |
| SCHEMBL4060945 | 0.81 | DHPS (0.71) | DHPS | |
| SCHEMBL4061454 | 0.81 | DHPS (0.83) | DHPS | |
| SCHEMBL7694584 | 0.79 | EDNRB (0.44) | DHPS | |
| SCHEMBL30410967 | 0.79 | DHPS (1.00) | DHPS | |
| SCHEMBL28573132 | 0.79 | DHPS (1.00) | DHPS | |
| SCHEMBL5763619 | 0.78 | EDNRB (0.66) | DHPS | |
| SCHEMBL9423908 | 0.77 | LMNA (0.55) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083650-A1 | NOVEL SULFONYLAMINO-PYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-10-24 | — | — | WO | disclosed |