Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 5/20 | 0.40 |
| ▸ | TDO2 | P48775 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952027 | 0.78 | POLB (0.50) | MAPTALDH1A1L3MBTL1IDO1TDO2 | |
| SCHEMBL7072166 | 0.76 | IDO1 (0.49) | MAPTALDH1A1L3MBTL1IDO1TDO2 | |
| SCHEMBL5275526 | 0.75 | MAPT (0.51) | MAPTALDH1A1L3MBTL1IDO1TDO2 | |
| SCHEMBL6951615 | 0.71 | IDO1 (0.41) | MAPTALDH1A1L3MBTL1IDO1TDO2 | |
| SCHEMBL6948710 | 0.71 | MAPT (0.42) | MAPTALDH1A1L3MBTL1IDO1TDO2 | |
| SCHEMBL7072168 | 0.71 | MAPT (0.36) | MAPTALDH1A1L3MBTL1IDO1TDO2 | |
| SCHEMBL20600322 | 0.70 | IDO1 (0.50) | MAPTALDH1A1L3MBTL1IDO1TDO2 | |
| SCHEMBL29567273 | 0.70 | IDO1 (0.50) | MAPTALDH1A1L3MBTL1IDO1TDO2 | |
| SCHEMBL87439 | 0.70 | IDO1 (0.50) | MAPTALDH1A1L3MBTL1IDO1TDO2 | |
| SCHEMBL31735796 | 0.70 | MAPT (0.47) | MAPTALDH1A1L3MBTL1IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002038543-A2 | 3-SUBSTITUTED OXINDOLE BETA 3 AGONISTS | ELI LILLY AND COMPANY (US) | 2002-05-16 | — | — | WO | disclosed |