Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.50 |
| ▸ | TDO2 | P48775 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20600322 | 1.00 | IDO1 (0.50) | IDO1TDO2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL29567273 | 1.00 | IDO1 (0.50) | IDO1TDO2MAPTALDH1A1L3MBTL1 | |
| Sulfuric Acid SCHEMBL29636505 | 0.92 | IDO1 (0.45) | IDO1TDO2MAPTALDH1A1L3MBTL1 | |
| Ether SCHEMBL7072164 | 0.86 | MAPT (0.54) | IDO1TDO2MAPTALDH1A1L3MBTL1 | |
| Oxindole SCHEMBL8636427 | 0.83 | AHR (0.64) | IDO1MAPTALDH1A1GSK3BCREBBP | |
| SCHEMBL28412785 | 0.81 | MAOA (0.46) | IDO1MAPTALDH1A1TDP1GAA | |
| SCHEMBL14281470 | 0.77 | GAA (0.42) | IDO1MAPTALDH1A1TDP1GAA | |
| SCHEMBL9899738 | 0.77 | IDO1 (0.53) | IDO1TDO2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL31589582 | 0.76 | LRRK2 (0.47) | IDO1MAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7513257 | 0.76 | LRRK2 (0.52) | IDO1MAPTALDH1A1L3MBTL1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459390-B | 3-Hydroxy oxindole derivative containing Z-type 1, 4-dicarbonyl olefin, and preparation method and application thereof | SUN YAT-SEN UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| US-12208088-B2 | Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof | GENENTECH, INC. (US) | 2025-01-28 | — | — | US | claimed |
| EP-4017281-B1 | PET FOOD COMPOSITIONS | HILLS PET NUTRITION INC (US) | 2024-08-28 | — | — | EP | claimed |
| CN-118459390-A | 3-Hydroxy oxindole derivative containing Z-type 1, 4-dicarbonyl olefin, and preparation method and application thereof | 中山大学 | 2024-08-09 | — | — | CN | claimed |
| CN-117486779-A | 3-hydroxy-2-oxindole compound and application thereof in preparation of antitumor drugs | 青岛海洋生物医药研究院股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-110156659-B | Preparation method of polyfluoro-substituted 3-hydroxyl oxindole compound | 上海应用技术大学 | 2022-10-14 | — | — | CN | claimed |
| EP-4017281-A1 | PET FOOD COMPOSITIONS | Hill's Pet Nutrition, Inc. (US) | 2022-06-29 | — | — | EP | claimed |
| WO-2021127701-A1 | PET FOOD COMPOSITIONS | HILL'S PET NUTRITION, INC. (US) | 2021-06-24 | — | — | WO | claimed |
| CN-106459029-A | Indolin-2-one or pyrrolo-pyridin-2-one derivatives | 豪夫迈·罗氏有限公司 | 2017-02-22 | — | — | CN | claimed |
| EP-2090571-B1 | Pyrimidine derivates, medicaments comprising them, their use and process of their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 2012-05-16 | — | — | EP | claimed |
| EP-1670772-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2006-06-21 | — | — | EP | claimed |
| US-20060100211-A1 | Pyrimidine derivatives | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-05-11 | — | — | US | claimed |
| WO-2006005609-A2 | SUBSTITUTED OXINDOL DERIVATIVES AND MEDICAMENTS CONTAINING THE SAME | ABBOTT GMBH & CO.KG (DE) | 2006-01-19 | — | — | WO | claimed |
| WO-2005030736-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2005-04-07 | — | — | WO | claimed |
| CN-1585787-A | Graft polymer with sidechains comprising nitrogen heterocycles | BASF AG (DE) | 2005-02-23 | — | — | CN | claimed |
| CN-1585786-A | Graft polymer with sidechains comprising nitrogen heterocycles | BASF AG (DE) | 2005-02-23 | — | — | CN | claimed |
| WO-2004100910-A1 | COSMETIC PRODUCT CONTAINING AT LEAST ONE POLYMER BASED ON MONOMERS COMPRISING NITROGEN HETEROCYCLES | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | WO | claimed |
| EP-1448645-A2 | GRAFT POLYMER WITH SIDECHAINS COMPRISING NITROGEN HETEROCYCLES | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-25 | — | — | EP | claimed |
| US-20030171359-A1 | Suitable for treatment of illnesses characterised by excessive or abnormal cell proliferation; viral, bacterial, fungal and/or parasitic infections, skin diseases, bone diseases, cardiovascular diseases | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-09-11 | — | — | US | claimed |
| WO-2003042262-A2 | GRAFT POLYMER WITH SIDECHAINS COMPRISING NITROGEN HETEROCYCLES | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12208088-B2 | Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof | HIPK1, NEK1, HIPK2 | IDO1 1487/4885TDO2 2682/4885MAPT 4740/4885 |
| US-20060100211-A1 | Pyrimidine derivatives | TYMP, TYMS, DPYD | IDO1 1245/4885TDO2 1356/4885MAPT 2061/4885 |
| US-20030171359-A1 | Suitable for treatment of illnesses characterised by excessive or abnormal cell proliferation; viral, bacterial, fungal and/or parasitic infections, skin diseases, bone diseases, cardiovascular diseases | COL1A1, MKI67, INSR | IDO1 363/4885TDO2 2546/4885MAPT 3134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.