Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.49 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685434 | 0.88 | NOX1 (0.38) | NOX1SNCAMAPTALOX15HSD17B10 | |
| SCHEMBL7690691 | 0.79 | SNCA (0.63) | NOX1SNCAMAPTMEN1KMT2A | |
| SCHEMBL7692247 | 0.77 | SNCA (0.45) | NOX1SNCAMAPTMEN1KMT2A | |
| SCHEMBL342918 | 0.73 | NOX1 (0.81) | NOX1SNCAMAPTMEN1KMT2A | |
| SCHEMBL7688195 | 0.72 | NOX1 (0.49) | NOX1MAPTMEN1KMT2AALOX15 | |
| SCHEMBL7690724 | 0.72 | MAPT (0.58) | NOX1MAPTMEN1KMT2AALOX15 | |
| SCHEMBL4707754 | 0.66 | NOX1 (0.68) | NOX1SNCAMAPTMEN1KMT2A | |
| SCHEMBL7690177 | 0.65 | ALDH1A1 (0.36) | NOX1MAPTALOX15HSD17B10 | |
| SCHEMBL4256305 | 0.64 | CA12 (0.44) | MAPTKMT2APGR | |
| SCHEMBL7692864 | 0.63 | NOX1 (0.39) | NOX1SNCAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002539202-A | — | — | 2002-11-19 | — | — | JP | claimed |
| EP-1163233-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-12-19 | — | — | EP | claimed |
| WO-2000055147-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-09-21 | — | — | WO | claimed |
| EP-1163233-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000055147-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-09-21 | — | — | WO | disclosed |