Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYBB | P04839 | 1/20 | 0.30 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.30 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.30 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929244 | 0.68 | ALDH1A1 (0.32) | ALDH1A1MAPTHPGDALOX15HSD17B10 | |
| SCHEMBL7695841 | 0.65 | NOX1 (0.49) | MAPTALOX15HSD17B10NOX1 | |
| SCHEMBL15958871 | 0.63 | TRPV4 (0.42) | ALDH1A1MAPTHPGDALOX15HSD17B10 | |
| SCHEMBL7692247 | 0.62 | SNCA (0.45) | MAPTALOX15HSD17B10NOX1 | |
| SCHEMBL27614015 | 0.62 | CYP11B1 (0.40) | — | |
| SCHEMBL28994625 | 0.62 | TRPV4 (0.54) | ALDH1A1MAPTHPGD | |
| SCHEMBL16327958 | 0.59 | PDE2A (0.41) | ALDH1A1MAPT | |
| SCHEMBL7688195 | 0.59 | NOX1 (0.49) | ALDH1A1MAPTHPGDALOX15HSD17B10 | |
| SCHEMBL13868312 | 0.58 | KDM4E (0.43) | ALDH1A1MAPTHPGDALOX15HSD17B10 | |
| SCHEMBL9314066 | 0.58 | CYP11B1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002539202-A | — | — | 2002-11-19 | — | — | JP | claimed |
| EP-1163233-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-12-19 | — | — | EP | claimed |
| WO-2000055147-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-09-21 | — | — | WO | claimed |
| EP-1163233-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000055147-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-09-21 | — | — | WO | disclosed |