Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699912 | 0.85 | NPY5R (0.60) | LMNAALDH1A1THRBNPY5RPOLB | |
| SCHEMBL7702562 | 0.84 | NPY5R (0.61) | LMNAALDH1A1THRBNPY5RTP53 | |
| SCHEMBL7698110 | 0.81 | NPY5R (0.50) | ALDH1A1THRBNPY5RPOLBTP53 | |
| SCHEMBL7700849 | 0.81 | ALDH1A1 (0.72) | LMNAALDH1A1THRBNPY5RPOLB | |
| SCHEMBL3406883 | 0.78 | GBA1 (0.60) | ALDH1A1RECQLNPY5RPOLBTP53 | |
| SCHEMBL15916076 | 0.72 | MAPT (0.56) | ALDH1A1RECQLNPY5RPOLBMAPT | |
| SCHEMBL14606680 | 0.72 | GBA1 (0.53) | ALDH1A1RECQLNPY5RPOLBMAPT | |
| SCHEMBL7702998 | 0.71 | MAPT (0.59) | ALDH1A1RECQLNPY5RPOLBMAPT | |
| SCHEMBL13797033 | 0.69 | GBA1 (0.47) | ALDH1A1RECQLNPY5RPOLBTP53 | |
| SCHEMBL7697188 | 0.68 | NPY5R (0.67) | LMNAALDH1A1THRBNPY5RPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057220-A1 | HYDRAZIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | claimed |
| WO-2002057220-A1 | HYDRAZIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |