Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702562 | 0.91 | NPY5R (0.61) | ALDH1A1LMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL7699912 | 0.90 | NPY5R (0.60) | ALDH1A1LMNAKMT2AMEN1NPY5R | |
| SCHEMBL7696113 | 0.81 | LMNA (0.47) | ALDH1A1LMNAKMT2AMEN1NPY5R | |
| SCHEMBL3853060 | 0.78 | ALDH1A1 (1.00) | ALDH1A1LMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL3851599 | 0.77 | NPY5R (0.68) | ALDH1A1LMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL3851498 | 0.77 | KMT2A (0.86) | ALDH1A1LMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL7698110 | 0.75 | NPY5R (0.50) | ALDH1A1NPY5RTHRBMAPTTP53 | |
| SCHEMBL7697188 | 0.74 | NPY5R (0.67) | ALDH1A1LMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL28676609 | 0.74 | ALDH1A1 (0.85) | ALDH1A1LMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL7698607 | 0.73 | KMT2A (0.58) | ALDH1A1LMNAKMT2AMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057220-A1 | HYDRAZIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |