Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701767 | 0.86 | POLB (0.53) | KMT2APOLBMEN1ALDH1A1LMNA | |
| SCHEMBL7696382 | 0.86 | L3MBTL1 (0.58) | KMT2APOLBMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7698666 | 0.81 | L3MBTL1 (0.44) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL7700875 | 0.80 | MEN1 (0.56) | KMT2APOLBMEN1ALDH1A1LMNA | |
| SCHEMBL7699803 | 0.80 | NPC1 (0.44) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL7700110 | 0.79 | KDM4E (0.44) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL7695579 | 0.79 | MEN1 (0.55) | KMT2APOLBMEN1ALDH1A1LMNA | |
| SCHEMBL7703801 | 0.79 | L3MBTL1 (0.49) | KMT2APOLBMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7699968 | 0.77 | ATM (0.49) | KMT2APOLBMEN1ALDH1A1LMNA | |
| SCHEMBL7695770 | 0.76 | MAPT (0.58) | ALDH1A1LMNAKDM4EL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |