Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694348 | 0.92 | HTR2C (0.38) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7700016 | 0.88 | IKBKB (0.42) | L3MBTL1HPGDKMT2ATSHRMAPT | |
| SCHEMBL7696382 | 0.86 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL7699803 | 0.86 | NPC1 (0.44) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7700110 | 0.86 | KDM4E (0.44) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7697060 | 0.83 | IKBKB (0.40) | L3MBTL1PDE10ALMNASMN1; SMN2IKBKB | |
| SCHEMBL7696239 | 0.81 | KMT2A (0.55) | L3MBTL1ALDH1A1KDM4EKMT2ANPC1 | |
| SCHEMBL7699801 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL7698990 | 0.79 | HTR2C (0.43) | ALDH1A1KDM4EHPGDKMT2ANPC1 | |
| SCHEMBL7703801 | 0.79 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KMT2ATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |