Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695579 | 0.92 | MEN1 (0.55) | MEN1KMT2APOLBNPSR1LMNA | |
| SCHEMBL7701767 | 0.84 | POLB (0.53) | MEN1KMT2APOLBLMNATSHR | |
| SCHEMBL7697994 | 0.80 | IKBKB (0.44) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL7696239 | 0.80 | KMT2A (0.55) | MEN1KMT2APOLBNPSR1LMNA | |
| SCHEMBL7701990 | 0.79 | IKBKB (0.46) | LMNASMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL7695134 | 0.78 | L3MBTL1 (0.48) | MEN1KMT2AMAPTTP53NPC1 | |
| SCHEMBL7699623 | 0.77 | AVPR2 (0.46) | MEN1KMT2APOLBNPSR1LMNA | |
| SCHEMBL7700263 | 0.76 | TP53 (0.47) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL30106352 | 0.75 | TACR3 (0.51) | MEN1KMT2APOLBNPSR1LMNA | |
| SCHEMBL7694358 | 0.75 | RXFP1 (0.41) | MEN1KMT2APOLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |