SCHEMBL7703801

SCHEMBL7703801

CN(C)c1ccc(-c2oc(-c3ccccc3-c3ccccc3)nc2C(=O)N2CCN(c3ccccc3)CC2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.49
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
POLB P06746 2/20 0.44
SLC6A7 Q99884 1/20 0.44
ALDH1A1 P00352 3/20 0.42
MAPT P10636 3/20 0.41
TP53 P04637 2/20 0.41
APOBEC3A P31941 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
SCD O00767 1/20 0.41
SCD5 Q86SK9 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CCKAR P32238 1/20 0.40
NAMPT P43490 1/20 0.39
USP2 O75604 1/20 0.39
TSHR P16473 1/20 0.39
ABL1 P00519 1/20 0.39
BCR P11274 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7696382 0.92 L3MBTL1 (0.58) L3MBTL1KMT2AMEN1POLBSLC6A7
SCHEMBL7699994 0.89 ATM (0.47) L3MBTL1KMT2AMEN1POLBALDH1A1
SCHEMBL7694348 0.87 HTR2C (0.38) L3MBTL1KMT2AMEN1ALDH1A1MAPT
SCHEMBL7698990 0.86 HTR2C (0.43) KMT2AMEN1ALDH1A1TP53TDP1
SCHEMBL7699217 0.86 MAPT (0.36) L3MBTL1KMT2AMEN1ALDH1A1MAPT
SCHEMBL7699968 0.81 ATM (0.49) L3MBTL1KMT2AMEN1POLBALDH1A1
SCHEMBL7695160 0.81 MAPT (0.41) KMT2AMEN1ALDH1A1MAPTTP53
SCHEMBL7702049 0.80 DGAT1 (0.47) L3MBTL1KMT2AMEN1POLBALDH1A1
SCHEMBL7698666 0.79 L3MBTL1 (0.44) L3MBTL1KMT2AMEN1ALDH1A1MAPT
SCHEMBL7694385 0.79 L3MBTL1 (0.58) L3MBTL1KMT2AMEN1POLBSLC6A7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002064558-A2 OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS SANKYO COMPANY, LIMITED (JP) 2002-08-22 WO disclosed