Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | SNCA | P37840 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456892 | 0.69 | HCAR2 (0.41) | TLK2ALDH1A1HSD17B10POLBTDP1 | |
| SCHEMBL22033216 | 0.69 | GAA (0.45) | L3MBTL1ALOX15ALDH1A1HSD17B10GAA | |
| SCHEMBL4731700 | 0.67 | PDPK1 (0.43) | L3MBTL1ALOX15ALDH1A1MAPK10HSD17B10 | |
| SCHEMBL918364 | 0.67 | SCN4A (0.52) | L3MBTL1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL29652613 | 0.66 | NOTUM (0.45) | TLK2ALOX15ALDH1A1MAPK10GAA | |
| Hydrochloric Acid SCHEMBL30014721 | 0.65 | SCN4A (0.50) | L3MBTL1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL9934356 | 0.64 | GAA (0.43) | L3MBTL1ALOX15ALDH1A1GAAMAPT | |
| SCHEMBL4787445 | 0.64 | SCN4A (0.48) | ALDH1A1MAPTMEN1KMT2AMAOA | |
| SCHEMBL9729916 | 0.64 | TLK2 (0.31) | TLK2 | |
| SCHEMBL3001981 | 0.63 | BRD4 (0.37) | TLK2ALOX15ALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358947-B1 | ANTITUMOR AND ANTICARCINOGENIC AGENTS; TREATING SEXUAL, UROGENITAL, AND HORMONAL DISORDERS; SIDE EFFECT REDUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-19 | — | — | US | disclosed |