Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081408 | 0.74 | GPR84 (0.33) | — | |
| SCHEMBL1456892 | 0.68 | HCAR2 (0.41) | TLK2 | |
| SCHEMBL28811874 | 0.68 | BACE1 (0.33) | — | |
| SCHEMBL28925359 | 0.66 | RPS6KA3 (0.31) | — | |
| SCHEMBL918364 | 0.66 | SCN4A (0.52) | — | |
| SCHEMBL9733028 | 0.65 | SMN1; SMN2 (0.49) | — | |
| Hydrochloric Acid SCHEMBL30014721 | 0.64 | SCN4A (0.50) | — | |
| SCHEMBL7696286 | 0.64 | L3MBTL1 (0.37) | TLK2 | |
| SCHEMBL4787445 | 0.63 | SCN4A (0.48) | — | |
| SCHEMBL15814177 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081242-A | Cardiotonic and bronchodilator agents; phosphodiesterase inhibitors | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0272914-A3 | 6-BENZOXAZINYL- AND 6-BENZOTHIAZINYL-2,3,4,5-TETRAHYDROPYRIDAZIN-3-ONES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1990-04-04 | — | — | EP | disclosed |
| US-4766118-A | CARDIOTONIC AGENTS, PHOSPHODIESTERASE INHIBITORS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0272914-A2 | 6-Benzoxazinyl- and 6-benzothiazinyl-2,3,4,5-tetrahydropyridazin-3-ones | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-06-29 | — | — | EP | disclosed |