Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 11/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700054 | 0.88 | NPC1 (0.50) | CETPKDM4EHPGDNPC1MAPT | |
| SCHEMBL7696225 | 0.87 | EPHX2 (0.45) | CETPKDM4EHPGDNPC1MAPT | |
| SCHEMBL7693513 | 0.86 | DGAT1 (0.48) | CETPKDM4EHPGDNPC1MAPT | |
| SCHEMBL7702160 | 0.86 | EPHX2 (0.44) | CETPNPC1RAB9AEPHX2 | |
| SCHEMBL7695821 | 0.86 | ECE1 (0.49) | CETPHPGDMAPTSMN1; SMN2CYP2C9 | |
| SCHEMBL7693795 | 0.86 | KDM4E (0.51) | KDM4ENPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7700202 | 0.86 | EPHX2 (0.52) | NPC1RAB9AEPHX2 | |
| SCHEMBL7696432 | 0.86 | CNR1 (0.43) | CETPMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7701069 | 0.86 | POLB (0.48) | CETPMAPTMLYCDEPHX2 | |
| SCHEMBL7700562 | 0.86 | ALDH1A1 (0.49) | CETPKDM4EHPGDNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |