Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700675 | 0.81 | MAPK14 (0.43) | NTRK1MAPK14 | |
| SCHEMBL7690441 | 0.78 | MAPK14 (0.47) | NTRK1MAPK14 | |
| SCHEMBL7691048 | 0.78 | MAPK14 (0.42) | MAPK14MEN1KMT2A | |
| SCHEMBL7691122 | 0.77 | MAPK14 (0.50) | MAPK14 | |
| SCHEMBL7697564 | 0.77 | MAPK14 (0.41) | NTRK1MAPK14 | |
| SCHEMBL7693923 | 0.77 | MAPK14 (0.45) | NTRK1MAPK14 | |
| SCHEMBL7694525 | 0.76 | MAPK14 (0.39) | NTRK1MAPK14 | |
| SCHEMBL7697861 | 0.76 | MAPK14 (0.47) | NTRK1MAPK14 | |
| SCHEMBL7696568 | 0.76 | MAPK14 (0.41) | NTRK1MAPK14 | |
| SCHEMBL7694572 | 0.74 | MAPT (0.39) | TP53NTRK1MAPK14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |