Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25195678 | 0.85 | PKM (0.45) | KMT2AMAPTPOLBNPC1ALDH1A1 | |
| SCHEMBL25220218 | 0.84 | ALDH1A1 (0.47) | KMT2AALDH1A1PKMMEN1TP53 | |
| SCHEMBL25210763 | 0.80 | KMT2A (0.48) | KMT2AMAPTPOLBRAB9ANPC1 | |
| SCHEMBL25206798 | 0.79 | ALDH1A1 (0.43) | KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL17863558 | 0.78 | KDM4E (0.54) | KMT2ALMNARAB9AMEN1TP53 | |
| SCHEMBL30417646 | 0.77 | CHRNA4 (0.46) | PKM | |
| SCHEMBL14703142 | 0.77 | KMT2A (0.41) | KMT2AMAPTLMNAHPGDRAB9A | |
| SCHEMBL5459563 | 0.76 | ALDH1A1 (0.55) | KMT2AMAPTLMNAEPHX2ALDH1A1 | |
| SCHEMBL5217325 | 0.76 | KDM4E (0.68) | KMT2ALMNAEPHX2ALDH1A1MEN1 | |
| SCHEMBL6559744 | 0.76 | KDM4E (0.68) | KMT2ALMNAEPHX2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |