Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA4 | P43681 | 15/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 14/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 14/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 14/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 10/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22636193 | 0.79 | P2RX7 (0.43) | — | |
| SCHEMBL25206798 | 0.77 | ALDH1A1 (0.43) | — | |
| SCHEMBL7696764 | 0.77 | KMT2A (0.51) | PKM | |
| SCHEMBL25220218 | 0.76 | ALDH1A1 (0.47) | PKM | |
| SCHEMBL25195678 | 0.74 | PKM (0.45) | PKM | |
| SCHEMBL25210763 | 0.72 | KMT2A (0.48) | PKM | |
| SCHEMBL30359179 | 0.71 | ALDH1A1 (0.45) | CHRNA4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18498223 | 0.70 | CHRNB2 (0.63) | CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL25436740 | 0.70 | GRIN2B (0.63) | HDAC2 | |
| SCHEMBL1914357 | 0.69 | GRIN2B (0.64) | CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452264-A1 | COMBINATION OF A TASK1/3 CHANNEL BLOCKER WITH A NOREPINEPHRINE REUPTAKE INHIBITOR FOR THE TREATMENT OF SLEEP APNEA | Bayer Aktiengesellschaft (DE) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023118126-A1 | COMBINATION OF A TASK1/3 CHANNEL BLOCKER WITH A NOREPINEPHRINE REUPTAKE INHIBITOR FOR THE TREATMENT OF SLEEP APNEA | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-29 | — | — | WO | disclosed |