SCHEMBL7697

SCHEMBL7697

O=C(O)CNc1ccccc1C(=O)c1cccc([N+](=O)[O-])c1[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CTSD P07339 1/20 0.43
ALDH1A1 P00352 4/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 2/20 0.43
KCNMA1 Q12791 1/20 0.42
RAB9A P51151 3/20 0.42
NPC1 O15118 1/20 0.42
GPR35 Q9HC97 1/20 0.41
TSHR P16473 1/20 0.40
POLB P06746 1/20 0.40
CXCR1 P25024 1/20 0.40
CXCR2 P25025 1/20 0.40
KAT2B Q92831 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
LMNA P02545 1/20 0.40
AGTR1 P30556 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3134716 0.89 CTSD (0.51) MEN1KMT2ACTSDALDH1A1GAA
SCHEMBL27770288 0.89 PARP1 (0.44) MEN1KMT2ACTSDALDH1A1GAA
SCHEMBL1653792 0.85 GPR35 (0.49) MEN1KMT2AALDH1A1GAAMAPT
SCHEMBL124292 0.80 MEN1 (0.60) MEN1KMT2AALDH1A1GAAMAPT
Hydrochloric Acid SCHEMBL6032002 0.80 MEN1 (0.60) MEN1KMT2AALDH1A1GAAMAPT
SCHEMBL8621506 0.80 MEN1 (0.46) MEN1KMT2ACTSDALDH1A1GAA
SCHEMBL7417028 0.80 GPR35 (0.60) CTSDALDH1A1KCNMA1GPR35TSHR
SCHEMBL2914635 0.80 CES2 (0.52) MEN1KMT2AALDH1A1GAAMAPT
SCHEMBL8624807 0.79 CTSD (0.46) MEN1KMT2ACTSDALDH1A1GAA
SCHEMBL27600331 0.77 CTSD (0.49) MEN1KMT2ACTSDALDH1A1GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4528 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5786428-A POLYMER MATRIX OF UNSATURATED MONOMER AND METAL COMPLEX HAVING A LIGAND AND A POLYMERIZABLE UNSATURATED MOIETY; EFFICIENT, RAPID AND SIMPLE PURIFICATION; MEDICAL DIAGNOSIS; CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-07-28 US claimed
CN-122094690-A Pharmaceutical composition comprising Maraglinib (MARALIXIBAT) and use thereof 2026-05-26 CN disclosed
CN-122071439-A Benzo-ring-containing compounds as protein tyrosine phosphatase inhibitors and uses thereof 湖北生物医药产业技术研究院有限公司 2026-05-22 CN disclosed
WO-2026103887-A1 PROLINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 北京康辰药业股份有限公司 2026-05-21 WO disclosed
WO-2026103853-A1 TSHR ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF 长春金赛药业有限责任公司 2026-05-21 WO disclosed
CN-122070482-A Methods of using neurofilament light chain immunoassays 美国西门子医学诊断股份有限公司 2026-05-19 CN disclosed
CN-122036731-A CB1 receptor inverse agonist compound, pharmaceutical composition, preparation method and application thereof 北京康辰药业股份有限公司 2026-05-15 CN disclosed
WO-2026102437-A1 METHODS OF TREATING FRAGILE X SYNDROME USING PDE4 INHIBITORS DART NEUROSCIENCE LLC (US) 2026-05-15 WO disclosed
CN-122055367-A 5-Oxo-4, 5-dihydroimidazo [1,5-a ] quinazoline compounds as PI3K [ alpha ] inhibitors 皮卡维森治疗学股份有限公司 2026-05-15 CN disclosed
CN-117659017-B TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof 北京华益健康药物研究中心 2026-05-15 CN disclosed
US-5532266-A Acrylacetamides MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1996-07-02 US disclosed
US-5360802-A Antagonists of cholecystokinin and gastrin MERCK SHARPE & DOHME LTD. 1994-11-01 US disclosed
US-5232978-A 1-(2-arylethyl)-pyrrolidines MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-08-03 US disclosed
EP-0514133-A1 Benzodiazepine derivatives, compositions containing them and their use in therapy MERCK SHARP & DOHME LTD. (GB) 1992-11-19 EP disclosed
US-5011995-A Hydrogenation of N-Aliphatic Keimines Using A Complex Iridium Catalyst CIBA-GEIGY CORPORATION (US) 1991-04-30 US disclosed
EP-0270595-B1 AN OPTICALLY ACTIVE REAGENT AND A METHOD FOR THE DETERMINATION OF ENANTIOMERIC AMINE COMPOUNDS EKA NOBEL AB (SE) 1990-08-16 EP disclosed
US-4855323-A Leukotriene antagonists, a process for the preparation thereof, and the use thereof for the treatment of diseases HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-08 US disclosed
US-4818704-A REACTING WITH FLUORENYL COMPOUND TO FORM CARBAMATE; SEPARATION BY LIQUID CHROMATOGRAPHY EKA NOBEL AB (SE) 1989-04-04 US disclosed
US-4788199-A ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS RHONE-POULENC SANTE (FR) 1988-11-29 US disclosed
US-4788204-A TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS RHONE-POULENC SANTE (FR) 1988-11-29 US disclosed