SCHEMBL7697179

SCHEMBL7697179

C=C(Cc1ccc(Cl)cc1)C(=O)OC

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
POLB P06746 1/20 0.47
CNR2 P34972 2/20 0.47
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
LMNA P02545 1/20 0.45
EGFR P00533 1/20 0.44
ERBB2 P04626 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
MAPT P10636 2/20 0.44
KLK7 P49862 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7696664 0.84 HPGD (0.45) ALDH1A1KMT2AMEN1L3MBTL1NPC1
SCHEMBL14541020 0.84 CA2 (0.48) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL7347631 0.83 MAPT (0.50) ALDH1A1POLBKMT2AMEN1L3MBTL1
SCHEMBL7689979 0.82 HTT (0.61) ALDH1A1POLBKMT2AMEN1NPC1
SCHEMBL8215730 0.82 L3MBTL1 (0.51) ALDH1A1KMT2AMEN1L3MBTL1LMNA
SCHEMBL8652955 0.82 KMT2A (0.48) ALDH1A1POLBKMT2AMEN1L3MBTL1
SCHEMBL1666500 0.81 CES2 (0.48) ALDH1A1POLBCNR2KMT2AMEN1
SCHEMBL7635599 0.81 ALDH1A1 (0.57) ALDH1A1POLBCNR2KMT2AMEN1
SCHEMBL7696588 0.81 L3MBTL1 (0.45) ALDH1A1POLBKMT2AMEN1L3MBTL1
SCHEMBL9513774 0.79 L3MBTL1 (0.49) ALDH1A1POLBCNR2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160572-B Ultraviolet-curable SiC ceramic precursor, preparation method and ceramic coating repair method 航天材料及工艺研究所 2024-02-09 CN claimed
US-6342627-B1 ESTER INTERCHANGE WITH ALCOHOL IN THE PRESENCE OF LANTHANOIDE METAL ALKOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-29 US disclosed