Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 7/20 | 0.40 |
| ▸ | KRAS | P01116 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 1/20 | 0.35 |
| ▸ | ATP4B | P51164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692125 | 0.82 | KDM4E (0.59) | LMNAHPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20867806 | 0.81 | KDM4E (0.44) | LMNAHPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6175013 | 0.80 | LMNA (0.47) | LMNAALDH1A1SOS1KRASCRHR1 | |
| SCHEMBL7691801 | 0.79 | HPGD (0.51) | LMNAHPGDKDM4EALDH1A1CRHR1 | |
| SCHEMBL7694007 | 0.79 | MAPT (0.55) | LMNAHPGDKDM4EALDH1A1CRHR1 | |
| SCHEMBL23809359 | 0.79 | ALOX15 (0.59) | LMNAHPGDKDM4EALDH1A1KCNK3 | |
| SCHEMBL13757342 | 0.78 | KDM4E (0.50) | LMNAHPGDKDM4EALDH1A1CRHR1 | |
| SCHEMBL7692631 | 0.78 | HPGD (0.50) | LMNAHPGDKDM4EALDH1A1EGFR | |
| SCHEMBL6177930 | 0.77 | ALOX15 (0.45) | LMNAHPGDKDM4EALDH1A1KCNK3 | |
| SCHEMBL7696145 | 0.74 | CRHR1 (0.48) | LMNAHPGDKDM4EALDH1A1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002026713-A1 | ANTIPARASITIC COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2002-04-04 | — | — | WO | disclosed |