Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696563 | 0.95 | POLB (0.61) | ALDH1A1PKMNPSR1CES2CES1 | |
| SCHEMBL21615871 | 0.93 | NAAA (0.61) | ALDH1A1PKMCES2CES1NAAA | |
| SCHEMBL3947433 | 0.93 | NAAA (0.61) | ALDH1A1PKMCES2CES1NAAA | |
| SCHEMBL1343140 | 0.93 | NAAA (0.61) | ALDH1A1PKMCES2CES1NAAA | |
| SCHEMBL3364793 | 0.89 | ALDH1A1 (0.58) | ALDH1A1PKMCES2CES1NAAA | |
| SCHEMBL8154519 | 0.85 | SOAT2 (0.67) | NPSR1NAAAPOLBLMNAMEN1 | |
| SCHEMBL27989558 | 0.85 | SOAT2 (0.67) | NPSR1NAAAPOLBLMNAMEN1 | |
| SCHEMBL10591379 | 0.84 | POLB (0.75) | ALDH1A1PKMCES2CES1NAAA | |
| SCHEMBL7263142 | 0.84 | HDAC1 (0.52) | ALDH1A1GAASMN1; SMN2LMNAMEN1 | |
| SCHEMBL28466752 | 0.83 | ALDH1A1 (0.55) | ALDH1A1PKMNPSR1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |