Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343140 | 1.00 | NAAA (0.61) | NAAAPOLBCES2CES1EPHX2 | |
| SCHEMBL3947433 | 1.00 | NAAA (0.61) | NAAAPOLBCES2CES1EPHX2 | |
| SCHEMBL5696563 | 0.98 | POLB (0.61) | NAAAPOLBCES2CES1EPHX2 | |
| SCHEMBL7697401 | 0.93 | ALDH1A1 (0.62) | NAAAPOLBCES2CES1MEN1 | |
| SCHEMBL27989558 | 0.91 | SOAT2 (0.67) | NAAAPOLBEPHX2MEN1KMT2A | |
| SCHEMBL8154519 | 0.91 | SOAT2 (0.67) | NAAAPOLBEPHX2MEN1KMT2A | |
| SCHEMBL29779165 | 0.89 | SMN1; SMN2 (0.57) | POLBCES2CES1EPHX2MEN1 | |
| SCHEMBL27581307 | 0.86 | HDAC1 (0.59) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL3364793 | 0.86 | ALDH1A1 (0.58) | NAAACES2CES1MEN1KMT2A | |
| SCHEMBL7270302 | 0.85 | HSD17B3 (0.63) | POLBKMT2AALDH1A1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321130-A1 | Senolytic Compositions and Uses Thereof | Rubedo Life Sciences, Inc. | 2023-10-12 | — | — | US | claimed |
| US-20210299154-A1 | Senolytic Compositions And Uses Thereof | Rubedo Life Sciences, Inc. | 2021-09-30 | — | — | US | claimed |
| EP-3790861-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | Rubedo Life Sciences, Inc. (US) | 2021-03-17 | — | — | EP | claimed |
| US-20200016185-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | Rubedo Life Sciences, Inc. | 2020-01-16 | — | — | US | claimed |
| CN-120153233-A | Device for visually registering excessive temperatures and method (option) for making same | 热力电子有限责任公司 | 2025-06-13 | — | — | CN | disclosed |
| US-20230321130-A1 | Senolytic Compositions and Uses Thereof | Rubedo Life Sciences, Inc. | 2023-10-12 | — | — | US | disclosed |
| US-20210299154-A1 | Senolytic Compositions And Uses Thereof | Rubedo Life Sciences, Inc. | 2021-09-30 | — | — | US | disclosed |
| US-11026963-B2 | Senolytic compositions and uses thereof | Rubedo Life Sciences, Inc. (US) | 2021-06-08 | — | — | US | disclosed |
| EP-3790861-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | Rubedo Life Sciences, Inc. (US) | 2021-03-17 | — | — | EP | disclosed |
| US-20200016185-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | Rubedo Life Sciences, Inc. | 2020-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210299154-A1 | Senolytic Compositions And Uses Thereof | SENP3, SENP6, SENP1 | NAAA 3752/4885POLB 422/4885CES2 4424/4885 |
| US-11026963-B2 | Senolytic compositions and uses thereof | SENP3, SENP6, SENP1 | NAAA 3752/4885POLB 422/4885CES2 4424/4885 |
| US-20200016185-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | SENP3, SENP6, SENP1 | NAAA 3752/4885POLB 422/4885CES2 4424/4885 |
| US-20230321130-A1 | Senolytic Compositions and Uses Thereof | SENP3, SENP6, SENP1 | NAAA 3752/4885POLB 422/4885CES2 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.