Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.81 |
| ▸ | HTT | P42858 | 6/20 | 0.81 |
| ▸ | BLM | P54132 | 6/20 | 0.81 |
| ▸ | MAPT | P10636 | 6/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.81 |
| ▸ | NPC1 | O15118 | 4/20 | 0.81 |
| ▸ | RAB9A | P51151 | 4/20 | 0.81 |
| ▸ | THRB | P10828 | 4/20 | 0.81 |
| ▸ | RECQL | P46063 | 4/20 | 0.81 |
| ▸ | POLB | P06746 | 3/20 | 0.81 |
| ▸ | PKM | P14618 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.81 |
| ▸ | APAF1 | O14727 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.81 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.81 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7697697 | 1.00 | MEN1 (0.81) | MEN1KMT2AHTTBLMMAPT | |
| SCHEMBL10036001 | 0.99 | NSD2 (0.81) | MEN1KMT2AHTTBLMMAPT | |
| SCHEMBL12311450 | 0.99 | NSD2 (0.81) | MEN1KMT2AHTTBLMMAPT | |
| SCHEMBL11670916 | 0.99 | NSD2 (0.81) | MEN1KMT2AHTTBLMMAPT | |
| Bromide SCHEMBL10431222 | 0.98 | NSD2 (0.80) | MEN1KMT2AHTTBLMMAPT | |
| Iodide SCHEMBL145357 | 0.90 | MEN1 (1.00) | MEN1KMT2AHTTBLMMAPT | |
| Iodide SCHEMBL5500973 | 0.90 | MEN1 (1.00) | MEN1KMT2AHTTBLMMAPT | |
| Iodide SCHEMBL145356 | 0.90 | MEN1 (1.00) | MEN1KMT2AHTTBLMMAPT | |
| SCHEMBL12611407 | 0.90 | NSD2 (0.83) | MEN1KMT2AHTTBLMMAPT | |
| SCHEMBL2409472 | 0.89 | NSD2 (1.00) | MEN1KMT2AHTTBLMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342329-B1 | Image-forming medium | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2002-01-29 | — | — | US | disclosed |
| EP-0930539-A1 | Image-forming medium | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 1999-07-21 | — | — | EP | disclosed |