SCHEMBL2409472

SCHEMBL2409472

CCN1C(=CC(C)=Cc2sc3ccccc3[n+]2CC)Sc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NSD2 O96028 1/20 1.00
▸ ALDH1A1 P00352 6/20 0.98
▸ MEN1 O00255 5/20 0.98
▸ KMT2A Q03164 5/20 0.98
▸ HTT P42858 5/20 0.98
▸ RAB9A P51151 5/20 0.98
▸ BLM P54132 4/20 0.98
▸ NPC1 O15118 4/20 0.98
▸ MAPT P10636 4/20 0.98
▸ POLB P06746 3/20 0.98
▸ APAF1 O14727 2/20 0.98
▸ THRB P10828 2/20 0.98
▸ PKM P14618 2/20 0.98
▸ RECQL P46063 2/20 0.98
▸ SMN1; SMN2 Q16637 2/20 0.98
▸ NPSR1 Q6W5P4 2/20 0.98
▸ TDP1 Q9NUW8 2/20 0.98
▸ PLA2G1B P04054 1/20 0.98
▸ MAPK1 P28482 1/20 0.98
▸ CDK5 Q00535 1/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349411 1.00 NSD2 (1.00) NSD2ALDH1A1MEN1KMT2AHTT
SCHEMBL10035965 1.00 NSD2 (1.00) NSD2ALDH1A1MEN1KMT2AHTT
SCHEMBL6426499 1.00 NSD2 (1.00) NSD2ALDH1A1MEN1KMT2AHTT
Iodide SCHEMBL145356 0.99 MEN1 (1.00) NSD2ALDH1A1MEN1KMT2AHTT
Iodide SCHEMBL145357 0.99 MEN1 (1.00) NSD2ALDH1A1MEN1KMT2AHTT
Iodide SCHEMBL5500973 0.99 MEN1 (1.00) NSD2ALDH1A1MEN1KMT2AHTT
Bromide SCHEMBL9192803 0.99 NSD2 (0.98) NSD2ALDH1A1MEN1KMT2AHTT
Hydrochloric Acid SCHEMBL9015126 0.99 NSD2 (0.98) NSD2ALDH1A1MEN1KMT2AHTT
Bromide SCHEMBL29362921 0.99 NSD2 (0.98) NSD2ALDH1A1MEN1KMT2AHTT
SCHEMBL12611407 0.91 NSD2 (0.83) NSD2ALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7771947-B2 Methods and compositions for rapid light-activated isolation and detection of analytes INVESTIGEN, INC. (US) 2010-08-10 — — US claimed
US-20080220436-A1 METHODS AND COMPOSITIONS FOR RAPID LIGHT-ACTIVATED ISOLATION AND DETECTION OF ANALYTES INVESTIGEN, INC. 2008-09-11 — — US claimed
WO-2008103702-A2 METHODS AND COMPOSITIONS FOR RAPID LIGHT-ACTIVATED ISOLATION AND DETECTION OF ANALYTES INVESTIGEN, INC. (US) 2008-08-28 — — WO claimed
EP-1263590-B1 THERMALLY IMAGEABLE ELEMENT AND LITHOGRAPHIC PRINTING PLATE KODAK POLYCHROME GRAPHICS CO (US) 2005-03-16 — — EP claimed
US-8021839-B2 Quantitative analysis; optical properties; kits INVESTIGEN, INC. (US) 2011-09-20 — — US disclosed
US-7771947-B2 Methods and compositions for rapid light-activated isolation and detection of analytes INVESTIGEN, INC. (US) 2010-08-10 — — US disclosed
EP-2010677-A2 METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDES Investigen, Inc. (US) 2009-01-07 — — EP disclosed
US-20080220436-A1 METHODS AND COMPOSITIONS FOR RAPID LIGHT-ACTIVATED ISOLATION AND DETECTION OF ANALYTES INVESTIGEN, INC. 2008-09-11 — — US disclosed
WO-2008103702-A2 METHODS AND COMPOSITIONS FOR RAPID LIGHT-ACTIVATED ISOLATION AND DETECTION OF ANALYTES INVESTIGEN, INC. (US) 2008-08-28 — — WO disclosed
US-20080096193-A1 Methods and compositions for detecting polynucleotides INVESTIGEN, INC. 2008-04-24 — — US disclosed
WO-2008041960-A2 METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDES INVESTIGEN, INC. (US) 2008-04-10 — — WO disclosed
US-20070231821-A1 Methods and compositions for detecting polynucleotides INVESTIGEN, INC. 2007-10-04 — — US disclosed
EP-0355661-A2 Direct positive image forming method FUJI PHOTO FILM CO., LTD. (JP) 1990-02-28 — — EP disclosed
EP-0318988-A1 Direct positive photographic light sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-06-07 — — EP disclosed
EP-0318987-A1 Direct positive photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-06-07 — — EP disclosed
EP-0315890-A1 Method for forming a direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1989-05-17 — — EP disclosed
EP-0283041-A1 Direct positive silver halide photosensitive material and method for forming direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1988-09-21 — — EP disclosed
US-4683192-A Silver halide photographic emulsions and process for producing them FUJI PHOTO FILM CO., LTD. (JP) 1987-07-28 — — US disclosed
US-3958991-A PHOTOCONDUCTOR EASTMAN KODAK COMPANY (US) 1976-05-25 — — US disclosed
US-3957492-A Photographic silver halide emulsion comprising an amphoteric copolymer FUJI PHOTO FILM CO., LTD. (JA) 1976-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070231821-A1 Methods and compositions for detecting polynucleotides POLN, POLRMT, POLH NSD2 4181/4885ALDH1A1 4773/4885MEN1 3712/4885
US-20080096193-A1 Methods and compositions for detecting polynucleotides POLN, POLRMT, POLH NSD2 4041/4885ALDH1A1 4743/4885MEN1 3230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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