Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | APAF1 | O14727 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | PLA2G1B | P04054 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 1/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL145357 | 1.00 | MEN1 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| Iodide SCHEMBL5500973 | 1.00 | MEN1 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL29349411 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2409472 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL10035965 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL6426499 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| Bromide SCHEMBL29362921 | 0.98 | NSD2 (0.98) | MEN1KMT2AHTTNPC1RAB9A | |
| Bromide SCHEMBL9192803 | 0.98 | NSD2 (0.98) | MEN1KMT2AHTTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9015126 | 0.98 | NSD2 (0.98) | MEN1KMT2AHTTNPC1RAB9A | |
| Iodide SCHEMBL7697694 | 0.90 | MEN1 (0.81) | MEN1KMT2AHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3149190-A1 | IDENTIFICATION OF NOVEL ANTI-PERSISTER ACTIVITY FOR BORRELIA BURGDORFERI | The Johns Hopkins University (US) | 2017-04-05 | — | — | EP | claimed |
| US-20170058314-A1 | NOVEL METHODOLOGY FOR IDENTIFYING ANTI-PERSISTER ACTIVITY AND ANTIMICROBIAL SUSCEPTIBILITY FOR BORRELIA BURGDORFERI AND OTHER BACTERIA | ZHANG YING (US) | 2017-03-02 | — | — | US | claimed |
| WO-2015171225-A1 | IDENTIFICATION OF NOVEL ANTI-PERSISTER ACTIVITY FOR BORRELIA BURGDORFERI | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-11-12 | — | — | WO | claimed |
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | claimed |
| US-4728796-A | Method for ionization of polymers | MEDICAL COLLEGE OF WISCONSIN (US) | 1988-03-01 | — | — | US | claimed |
| US-20250213601-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES | Didenko, Kirill (US) | 2025-07-03 | — | — | US | disclosed |
| EP-3478792-B1 | CHEMILUMINESCENT SUBSTRATES | BECKMAN COULTER INC (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2023187599-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES | DIDENKO KIRILL (MX) | 2023-10-05 | — | — | WO | disclosed |
| US-20230150960-A1 | COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA | UNIV JEFFERSON (US) | 2023-05-18 | — | — | US | disclosed |
| US-10703971-B2 | Chemiluminescent substrates | BECKMAN COULTER, INC. (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190161675-A1 | CHEMILUMINESCENT SUBSTRATES | BECKMAN COULTER, INC. (US) | 2019-05-30 | — | — | US | disclosed |
| EP-3478792-A1 | CHEMILUMINESCENT SUBSTRATES | Beckman Coulter Inc. (US) | 2019-05-08 | — | — | EP | disclosed |
| US-6139782-A | A CHEMILUMINESCENT CONTAINING A HETEROCYCLIC RING GROUP AND AN ENOL PHOSPHATE GROUP WHICH REACT WITH OXYGEN UPON REMOVAL OF PHOSPHATE GROUP WITH A PHOSPHATASE ENZYME TO PRODUCE AN ENOLATE WHICH REACTS WITH TO PRODUCE CHEMILUMINOESCENCE | LUMIGEN, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| US-6090571-A | REACTING PHOSPHATASE WITH NITROGEN-CONTAINING HETEROCYCLIC RING SYSTEM HAVING AN ENOL PHOSPHATE GROUP, DETECTING THE CHEMILUMINESCENCE, AND RELATING TO AMOUNT OF ANALYTE | LUMIGEN, INC. (US) | 2000-07-18 | — | — | US | disclosed |
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | disclosed |
| US-6045727-A | NITROGEN CONTAINING HETEROCYCLIC RING SYSTEM BEARING AN EXOCYCLIC CARBON-CARBON DOUBLE BOND. THE DOUBLE BOND IS FURTHER SUBSTITUTED AT THE DISTAL CARBON WITH A PHOSPHATE GROUP AND AN OXYGEN OR SULFUR ATOM-CONTAINING GROUP. | LUMIGEN, INC. (US) | 2000-04-04 | — | — | US | disclosed |
| EP-0819119-A4 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN INC (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0819119-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1997026245-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1997-07-24 | — | — | WO | disclosed |
| US-4728796-A | Method for ionization of polymers | MEDICAL COLLEGE OF WISCONSIN (US) | 1988-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150960-A1 | COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA | TFAM, COX5A, UQCRC1 | MEN1 2633/4885KMT2A 3675/4885HTT 2179/4885 |
| US-20250213601-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES | ACE2, FURIN, SARS1 | MEN1 732/4885KMT2A 2058/4885HTT 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.